Pathology of Wilms' tumour in International Society of Paediatric Oncology (SIOP) and Children's oncology group (COG) renal tumour studies: similarities and …

GM Vujanić, LN Parsons, E D'Hooghe… - …, 2022 - Wiley Online Library
Excellent outcomes for patients with Wilms' tumour (WT),> 90% for all stages together, have
been achieved through researching WT in multicentre and multinational trials and studies in …

Surgery for the complex Wilms tumour

S Cox, C Büyükünal, AJW Millar - Pediatric Surgery International, 2020 - Springer
The prognosis of children with Wilms tumour has greatly improved since the introduction of
adjuvant radiotherapy and chemotherapy more than 70 years ago with a current overall long …

Actinobacteria from Antarctica as a source for anticancer discovery

LJ Silva, EJ Crevelin, DT Souza, GV Lacerda-Júnior… - Scientific reports, 2020 - nature.com
Although many advances have been achieved to treat aggressive tumours, cancer remains
a leading cause of death and a public health problem worldwide. Among the main …

Late health outcomes among survivors of Wilms tumor diagnosed over three decades: a report from the Childhood Cancer Survivor Study

BR Weil, AJ Murphy, Q Liu, RM Howell… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE To evaluate long-term morbidity and mortality among unilateral, nonsyndromic
Wilms tumor (WT) survivors according to conventional treatment regimens. METHODS …

MMP-9 secreted by M2-type macrophages promotes Wilms' tumour metastasis through the PI3K/AKT pathway

K Tian, G Du, X Wang, X Wu, L Li, W Liu… - Molecular Biology Reports, 2022 - Springer
Background Wilms' tumour (WT) is a malignant tumour of childhood with the typical
symptoms of an abdominal mass. Tumour-associated macrophages (TAMs) accumulate and …

Late kidney effects of nephron-sparing vs radical nephrectomy for Wilms tumor: a systematic review and meta-analysis

A Khondker, A Jain, ML Groff, J Brzezinski… - The Journal of …, 2022 - auajournals.org
Purpose: We compare differences in long-term kidney function between patients undergoing
either radical nephrectomy (RN) or nephron-sparing surgery (NSS) in unilateral and bilateral …

Insights into personalized care strategies for Wilms tumor: A narrative literature review

S Karam, A Gebreil, A Alksas, HM Balaha, A Khalil… - Biomedicines, 2024 - mdpi.com
Wilms tumor (WT), or nephroblastoma, is the predominant renal malignancy in the pediatric
population. This narrative review explores the evolution of personalized care strategies for …

METTL14 gene polymorphisms decrease Wilms tumor susceptibility in Chinese children

Z Zhuo, RX Hua, H Zhang, H Lin, W Fu, J Zhu, J Cheng… - BMC cancer, 2021 - Springer
Background Wilms tumor is a highly heritable malignancy. Aberrant METTL14, a critical
component of N6-methyladenosine (m 6 A) methyltransferase, is involved in carcinogenesis …

Radical nephroureterectomy for pediatric unilateral renal tumor

JH Aldrink, R Romao, PF Ehrlich, E Tracy… - Seminars in Pediatric …, 2023 - Elsevier
Risk based therapy is a key element to successful treatment of a child with a renal tumor. 1
The surgeon plays an important role in accurately staging the disease which is essential to …

Relationship of tumour-associated macrophages with poor prognosis in Wilms' tumour

K Tian, X Wang, Y Wu, X Wu, G Du, W Liu… - Journal of Pediatric …, 2020 - Elsevier
Background Wilms' tumour (WT) is the most common childhood renal tumour. Tumour-
associated macrophages (TAMs) are a critical component of tumour microenvironments and …