Background: Despite an increasing body of research highlighting their efficacy to treat a
broad range of medical conditions, psychedelic drugs remain a controversial issue among …

The psychedelic effects of some plants and fungi have been known and deliberately
exploited by humans for thousands of years. Fungi, particularly mushrooms, are the principal …

Background Psilocybin has been suggested as a novel, rapid-acting treatment for
depression. Two consecutive doses have been shown to markedly decrease symptom …

Growing interest has been seen in using lysergic acid diethylamide (LSD) and psilocybin in
psychiatric research and therapy. However, no modern studies have evaluated differences …

The purpose of this paper is to provide an integrative review and offer novel insights
regarding human research with classic psychedelics (classic hallucinogens), which are …

Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …

Psilocybin can occasion mystical-type experiences with participant-attributed increases in
well-being. However, little research has examined enduring changes in traits. This study …

Responses to psychedelics are notoriously difficult to predict, yet significant work is currently
underway to assess their therapeutic potential and the level of interest in psychedelics …

Importance Bipolar II disorder (BDII) is a debilitating condition frequently associated with
difficult-to-treat depressive episodes. Psilocybin has evidence for rapid-acting …