Multiple sclerosis (MS) is a chronic, progressive disorder of the central nervous system
(CNS) that affects more than two million people worldwide. Several animal models resemble …

Persistent neuroinflammation is now recognized as a chief pathological component of
practically all neurodegenerative diseases. Neuroinflammation in the central nervous …

Vitamin D exerts multiple immunomodulatory functions and has been implicated in the
etiology and treatment of several autoimmune diseases, including multiple sclerosis (MS) …

An unmet but urgent medical need is the development of myelin repair promoting therapies
for Multiple Sclerosis (MS). Many such therapies have been pre-clinically tested using …

Insufficient remyelination due to impaired oligodendrocyte precursor cell (OPC)
differentiation and maturation is strongly associated with irreversible white matter injury …

Thyroid hormone plays an important role in central nervous system (CNS) development,
including the myelination of variable axonal calibers. It is well-established that thyroid …

Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central
nervous system. MS likely results from a complex interplay between predisposing causal …

Neurodegenerative diseases are characterized by chronic neuronal and/or glial cell loss,
while traumatic injury is often accompanied by the acute loss of both. Multipotent neural …

Background Neurodevelopmental disorders are increasing in prevalence worldwide.
Previous work suggests that exposure to the environmental air pollutant and greenhouse …

Multiple sclerosis (MS), a chronic inflammatory demyelinating and neurodegenerative
disease of the central nervous system, is today a leading cause of unpredictable lifelong …