During the past several years there has been extensive development and application of
hyperpolarized helium‐3 (HP 3He) magnetic resonance imaging (MRI) in clinical respiratory …

Pulmonary x‐ray computed tomographic (CT) and magnetic resonance imaging (MRI)
research and development has been motivated, in part, by the quest to subphenotype …

In subjects with chronic obstructive pulmonary disease (COPD), hyperpolarized xenon-129
(129Xe) magnetic resonance imaging (MRI) reveals significantly greater ventilation defects …

Clinical magnetic resonance imaging of the lung is technologically challenging, yet over the
past two decades hyperpolarized noble gas (3He and 129Xe) imaging has demonstrated …

Imaging of the lungs in patients with asthma has evolved dramatically over the last decade
with sophisticated techniques, such as computed tomography, magnetic resonance imaging …

Basic physical concepts of diffusion, convection, and dispersion pertaining to gas transport
in the human airways are reviewed. Their incorporation into quantitative models of gas …

The introduction of hyperpolarized gases (3He and 129Xe) has opened the door to
applications for which gaseous agents are uniquely suited—lung MRI. One of the pulmonary …

Hyperpolarized noble gas (3He and 129Xe) apparent diffusion coefficient (ADC)
measurements have shown remarkable sensitivity to microstructural (ie, alveolar) changes …

Lung imaging using conventional 1H MRI presents great challenges because of the low
density of lung tissue, lung motion and very fast lung tissue transverse relaxation (typical T2 …

The objective of this study was to evaluate the regional effects of bronchodilator
administration in chronic obstructive pulmonary disease (COPD) using hyperpolarized …