Aging attenuates the overall responsiveness of the immune system to eradicate pathogens.
The increased production of pro-inflammatory cytokines by innate immune cells under basal …

Sex differences are present in brain morphology, sex hormones, aging processes and
immune responses. These differences need to be considered for proper modelling of …

The putative pathogenic roles and therapeutic potential of the chaperone system (CS) in
amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) are reviewed to provide a …

Immunosenescence and chronic inflammation associated with old age accompany brain
aging and the loss of complex behaviors. Neuroinflammation in the hippocampus plays a …

Neurological disorders are highly prevalent and often lead to chronic debilitating disease.
Neuroinflammation is a major driver across the spectrum of disorders, and microglia are key …