Meningeal immunity and its function in maintenance of the central nervous system in health and disease
K Alves de Lima, J Rustenhoven… - Annual review of …, 2020 - annualreviews.org
Neuroimmunology, albeit a relatively established discipline, has recently sparked numerous
exciting findings on microglia, the resident macrophages of the central nervous system …
exciting findings on microglia, the resident macrophages of the central nervous system …
Multifaceted interactions between adaptive immunity and the central nervous system
J Kipnis - Science, 2016 - science.org
Neuroimmunologists seek to understand the interactions between the central nervous
system (CNS) and the immune system, both under homeostatic conditions and in diseases …
system (CNS) and the immune system, both under homeostatic conditions and in diseases …
The resolution of neuroinflammation in neurodegeneration: leukocyte recruitment via the choroid plexus
M Schwartz, K Baruch - The EMBO journal, 2014 - embopress.org
Inflammation is an integral part of the body's physiological repair mechanism, unless it
remains unresolved and becomes pathological, as evident in the progressive nature of …
remains unresolved and becomes pathological, as evident in the progressive nature of …
Inflammation in neurodegenerative disease—a double-edged sword
T Wyss-Coray, L Mucke - Neuron, 2002 - cell.com
Inflammation is a defense reaction against diverse insults, designed to remove noxious
agents and to inhibit their detrimental effects. It consists of a dazzling array of molecular and …
agents and to inhibit their detrimental effects. It consists of a dazzling array of molecular and …
Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury
DJ Donnelly, PG Popovich - Experimental neurology, 2008 - Elsevier
Trauma to the central nervous system (CNS) triggers intraparenchymal inflammation and
activation of systemic immunity with the capacity to exacerbate neuropathology and …
activation of systemic immunity with the capacity to exacerbate neuropathology and …
How and why do T cells and their derived cytokines affect the injured and healthy brain?
The evolution of adaptive immunity provides enhanced defence against specific pathogens,
as well as homeostatic immune surveillance of all tissues. Despite being'immune privileged' …
as well as homeostatic immune surveillance of all tissues. Despite being'immune privileged' …
T cell deficiency leads to cognitive dysfunction: implications for therapeutic vaccination for schizophrenia and other psychiatric conditions
The effects of the adaptive immune system on the cognitive performance and abnormal
behaviors seen in mental disorders such as schizophrenia have never been documented …
behaviors seen in mental disorders such as schizophrenia have never been documented …
The immunological response to traumatic brain injury
Traumatic brain injury (TBI) is the leading cause of death and disability in young adults in the
developed world. The accuracy of early outcome-prediction remains poor even when all …
developed world. The accuracy of early outcome-prediction remains poor even when all …
Degenerative and regenerative mechanisms governing spinal cord injury
C Profyris, SS Cheema, DW Zang, MF Azari… - Neurobiology of …, 2004 - Elsevier
Spinal cord injury (SCI) is a major cause of disability, and at present, there is no universally
accepted treatment. The functional decline following SCI is contributed to both direct …
accepted treatment. The functional decline following SCI is contributed to both direct …
Neuroinflammation, oxidative stress, and the pathogenesis of Parkinson's disease
RL Mosley, EJ Benner, I Kadiu, M Thomas… - Clinical neuroscience …, 2006 - Elsevier
Neuroinflammatory processes play a significant role in the pathogenesis of Parkinson's
disease (PD). Epidemiologic, animal, human, and therapeutic studies all support the …
disease (PD). Epidemiologic, animal, human, and therapeutic studies all support the …