Central nervous system (CNS) disease is one of the most important causes of human death.
Because of their complex pathogenesis, more and more attention has been paid to them. At …

Abstract Cryptolepine (1, 5-methyl-10 H-indolo [3, 2-b] quinoline), an indoloquinoline
alkaloid, found in the roots of Cryptolepis sanguinolenta (Lindl.) Schltr (family …

Some biochemical properties including phenolic content, anticholinergic, antidiabetic, and
antioxidant activities of Stachys annua were determined in this study. The methanol extract …

Inspired by the widely antiphytopathogenic application of diversified derivatives from natural
sources, cryptolepine and its derivatives were subsequently designed, synthesized, and …

New compounds containing thiazole and pyridinium moieties were designed and
synthesized. The potency of the synthesized compounds as selective inhibitors of …

The complex and multifaceted nature of Alzheimer's disease has brought about a pressing
demand to develop ligands targeting multiple pathways to combat its outrageous …

Natural products have extensively contributed toward the discovery of new leads for
Alzheimer's disease. During our search for new inhibitors of cholinesterase enzymes from …

The bio-constituents of medicinal plants are greatly influenced by the environmental
conditions and growing seasons. This study aimed to uncover the presence of different …

Due to their low cost, toxicity, and health risks, medicinal plants have come to be seen as
useful products and sources of biologically active compounds. Mangifera indica L., a …

The cholinesterase enzymes play a vital role in maintaining balanced levels of the
neurotransmitter acetylcholine in the central nervous system. However, the overexpression …