Imbalanced GSH/ROS and sequential cell death
T Liu, L Sun, Y Zhang, Y Wang… - Journal of Biochemical …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) are produced in cells during metabolic processes.
Excessive intracellular ROS may react with large biomolecules, such as DNA, RNA …
Excessive intracellular ROS may react with large biomolecules, such as DNA, RNA …
Toxicology and pharmacology of synthetic organoselenium compounds: An update
Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …
compounds and some naturally occurring organoselenium amino acids. The use of …
[HTML][HTML] Metal-based compounds containing selenium: An appealing approach towards novel therapeutic drugs with anticancer and antimicrobial effects
S Ramos-Inza, D Plano, C Sanmartín - European Journal of Medicinal …, 2022 - Elsevier
In recent years, both metal-based complexes and selenium-containing compounds have
been widely explored for their therapeutic properties due to their roles in biological …
been widely explored for their therapeutic properties due to their roles in biological …
Enzyme-Responsive COF-based thiol-targeting nanoinhibitor for curing bacterial infections
X Wang, B Sun, Z Ye, W Zhang, W Xu… - … Applied Materials & …, 2022 - ACS Publications
Pathogen infections impose severe challenges in clinical practice, especially for patients
infected with antibiotic-resistant microbes. The thioredoxin (Trx) system in Gram-positive …
infected with antibiotic-resistant microbes. The thioredoxin (Trx) system in Gram-positive …
Ebselen optimized the therapeutic effects of silver nanoparticles for periodontal treatment
Y Liang, B Wang, Q Yu, W Wang, S Ge… - International Journal of …, 2023 - Taylor & Francis
Objective Silver nanoparticles (AgNPs) possess excellent antibacterial effects on
periodontal pathogens, but their clinical application is limited mainly due to their cytotoxicity …
periodontal pathogens, but their clinical application is limited mainly due to their cytotoxicity …
Repurposing high-throughput screening identifies unconventional drugs with antibacterial and antibiofilm activities against Pseudomonas aeruginosa under …
G Di Bonaventura, V Lupetti, A Di Giulio… - Microbiology …, 2023 - Am Soc Microbiol
Pseudomonas aeruginosa is the most common pathogen infecting cystic fibrosis (CF) lungs,
causing acute and chronic infections. Intrinsic and acquired antibiotic resistance allow P …
causing acute and chronic infections. Intrinsic and acquired antibiotic resistance allow P …
Disruption of Bacterial Thiol-Dependent Redox Homeostasis by Magnolol and Honokiol as an Antibacterial Strategy
Y Ouyang, X Tang, Y Zhao, X Zuo, X Ren, J Wang… - Antioxidants, 2023 - mdpi.com
Some traditional Chinese medicines (TCMs) possess various redox-regulation properties,
but whether the redox regulation contributes to antibacterial mechanisms is not known …
but whether the redox regulation contributes to antibacterial mechanisms is not known …
Ebselen, a multi-target compound: its effects on biological processes and diseases
Q Lu, Y Cai, C Xiang, T Wu, Y Zhao, J Wang… - Expert Reviews in …, 2021 - cambridge.org
Ebselen is a well-known synthetic compound mimicking glutathione peroxidase (GPx),
which catalyses some vital reactions that protect against oxidative damage. Based on a …
which catalyses some vital reactions that protect against oxidative damage. Based on a …
The Assessment on Synergistic Activity of Ebselen and Silver Ion Against Yersinia pseudotuberculosis
C Dong, W Chen, L Zou, B Liu, K Deng, D Guo… - Frontiers in …, 2022 - frontiersin.org
Yersinia pseudotuberculosis is a foodborne zoonotic bacterium that is pathogenic to guinea
pigs, rabbits, and mice. It also causes pseudotuberculosis in humans. However, it still lacked …
pigs, rabbits, and mice. It also causes pseudotuberculosis in humans. However, it still lacked …
Selenosalicylate; a little-studied heavy-element analogue of the versatile thiosalicylate ligand
S Atiga, GC Saunders, W Henderson - RSC advances, 2024 - pubs.rsc.org
Selenosalicylic acid (ortho-HSeC6H4CO2H), the heavy element congener of the widely
studied thiosalicylic acid, was prepared by reaction of 2-carboxybenzenediazonium chloride …
studied thiosalicylic acid, was prepared by reaction of 2-carboxybenzenediazonium chloride …