Central neuronal activation and pressor responses induced by circulating ANG II: role of the brain aldosterone-“ouabain” pathway

BS Huang, S Ahmadi, M Ahmad… - American Journal …, 2010 - journals.physiology.org
An increase in plasma ANG II causes neuronal activation in hypothalamic nuclei and a slow
pressor response, presumably by increasing sympathetic drive. We evaluated whether the …

Cerebrospinal fluid hypernatremia elevates sympathetic nerve activity and blood pressure via the rostral ventrolateral medulla

SD Stocker, SM Lang, SS Simmonds, MM Wenner… - …, 2015 - Am Heart Assoc
Elevated NaCl concentrations of the cerebrospinal fluid increase sympathetic nerve activity
(SNA) in salt-sensitive hypertension. Neurons of the rostral ventrolateral medulla (RVLM) …

Pattern of neuronal activation in rats with CHF after myocardial infarction

F Vahid-Ansari, FHH Leenen - American Journal of …, 1998 - journals.physiology.org
To identify neuronal populations possibly contributing to the sympathetic hyperactivity in rats
with congestive heart failure (CHF) after myocardial infarction (MI), immunohistochemical …

Fos-related antigen immunoreactivity after acute and chronic angiotensin II–induced hypertension in the rabbit brain

PJ Davern, GA Head - Hypertension, 2007 - Am Heart Assoc
Several brain regions are proposed as contributing to chronic sympatho-excitatory effects of
elevated circulating angiotensin II. However, earlier c-Fos studies have been limited to acute …

Increases in brain and cardiac AT1 receptor and ACE densities after myocardial infarct in rats

J Tan, H Wang, FHH Leenen - American Journal of …, 2004 - journals.physiology.org
In the brain, ouabain-like compounds (OLC) and the reninangiotensin system (RAS)
contribute to sympathetic hyperactivity in rats after myocardial infarction (MI). This study …

Sustained activation of the central baroreceptor pathway in angiotensin hypertension

TE Lohmeier, JR Lohmeier, S Warren, PJ May… - …, 2002 - Am Heart Assoc
Recent studies indicate that renal sympathetic nerve activity is chronically suppressed in
angiotensin (Ang II) hypertension and that baroreflexes play a critical role in mediating this …

Sustained activation of the central baroreceptor pathway in obesity hypertension

TE Lohmeier, S Warren, JT Cunningham - Hypertension, 2003 - Am Heart Assoc
The major goal of this study was to determine whether there is increased activation of
medullary neurons that participate in the central baroreceptor reflex pathway in dogs with …

Renal denervation attenuates hypertension but not salt sensitivity in ETB receptor-deficient rats

BK Becker, AC Feagans, D Chen… - American Journal …, 2017 - journals.physiology.org
Hypertension is a prevalent pathology that increases risk for numerous cardiovascular
diseases. Because the etiology of hypertension varies across patients, specific and effective …

Chronic activation of brain areas by high-sodium diet in Dahl salt-sensitive rats

AS Budzikowski, F Vahid-Ansari… - American Journal of …, 1998 - journals.physiology.org
To map changes in neuronal activity in the brains of Dahl salt-sensitive (Dahl S) vs. salt-
resistant (Dahl R) rats by high-sodium diet, we used immunohistochemical detection of Fra …

Identification of active central nervous system sites in renal wrap hypertensive rats

JT Cunningham, M Herrera-Rosales, MA Martinez… - …, 2007 - Am Heart Assoc
To identify central neurons participating in cardiovascular regulation in hypertension, we
studied Fos staining, a marker for synaptically activated neurons, in adult male normotensive …