Co-culture approaches for cultivated meat production
The need and demand for sustainable, nutritious and animal-welfare-conscious meat
substitutes has spurred research into cultivated meat production. Meat mainly contains …
substitutes has spurred research into cultivated meat production. Meat mainly contains …
[HTML][HTML] Efficient differentiation of bone marrow mesenchymal stem cells into endothelial cells in vitro
C Wang, Y Li, M Yang, Y Zou, H Liu, Z Liang… - European Journal of …, 2018 - Elsevier
Objective Endothelial cells (ECs) play an important role in neovascularisation, but are too
limited in number for adequate therapeutic applications. Mesenchymal stem cells (MSCs) …
limited in number for adequate therapeutic applications. Mesenchymal stem cells (MSCs) …
[HTML][HTML] Optimization of co-culture conditions for a human vascularized adipose tissue model
In vitro adipose tissue models can be used to provide insight into fundamental aspects of
adipose physiology. These systems may serve as replacements for animal models, which …
adipose physiology. These systems may serve as replacements for animal models, which …
Cell‐derived and enzyme‐based decellularized extracellular matrix exhibit compositional and structural differences that are relevant for its use as a biomaterial
S Nellinger, I Mrsic, S Keller, S Heine… - Biotechnology and …, 2022 - Wiley Online Library
Due to its availability and minimal invasive harvesting human adipose tissue‐derived
extracellular matrix (dECM) is often used as a biomaterial in various tissue engineering and …
extracellular matrix (dECM) is often used as a biomaterial in various tissue engineering and …
[HTML][HTML] Construction of vascularized tissue-engineered breast with dual angiogenic and adipogenic micro-tissues
R Ni, C Luo, H Ci, D Sun, R An, Z Wang, J Yang, Y Li… - Materials Today Bio, 2023 - Elsevier
Hydrogel-based micro-tissue engineering technique, a bottom-up approach, is promising in
constructing soft tissue of large size with homogeneous spatial distribution and superior …
constructing soft tissue of large size with homogeneous spatial distribution and superior …
[HTML][HTML] PFKFB3-mediated glycometabolism reprogramming modulates endothelial differentiation and angiogenic capacity of placenta-derived mesenchymal stem …
Y Zhang, Y Zhong, W Liu, F Zheng, Y Zhao… - Stem cell research & …, 2022 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have a great potential ability for
endothelial differentiation, contributing to an effective means of therapeutic angiogenesis …
endothelial differentiation, contributing to an effective means of therapeutic angiogenesis …
Comparing the use of differentiated adipose-derived stem cells and mature adipocytes to model adipose tissue in vitro
AC Volz, B Omengo, S Gehrke, PJ Kluger - Differentiation, 2019 - Elsevier
In vitro models of human adipose tissue may serve as beneficial alternatives to animal
models to study basic biological processes, identify new drug targets, and as soft tissue …
models to study basic biological processes, identify new drug targets, and as soft tissue …
[HTML][HTML] Organ-on-a-disc: A platform technology for the centrifugal generation and culture of microphysiological 3D cell constructs amenable for automation and …
S Schneider, F Erdemann, O Schneider… - APL …, 2020 - pubs.aip.org
ABSTRACT Organ-on-a-chip (OoC) systems have evolved to a promising alternative to
animal testing and traditional cell assays in drug development and enable personalization …
animal testing and traditional cell assays in drug development and enable personalization …
Interactions of methacryloylated gelatin and heparin modulate physico-chemical properties of hydrogels and release of vascular endothelial growth factor
C Claaßen, A Southan, J Grübel, GEM Tovar… - Biomedical …, 2018 - iopscience.iop.org
Gelatin hydrogels are used as tissue engineering scaffolds and systems for controlled
release due to their inherent biodegradability and biocompatibility. In this study gelatin …
release due to their inherent biodegradability and biocompatibility. In this study gelatin …
Adipose stem cell‐derived extracellular matrix represents a promising biomaterial by inducing spontaneous formation of prevascular‐like structures by mvECs
S Nellinger, I Schmidt, S Heine… - Biotechnology and …, 2020 - Wiley Online Library
Tissue constructs of physiologically relevant scale require a vascular system to maintain cell
viability. However, in vitro vascularization of engineered tissues is still a major challenge …
viability. However, in vitro vascularization of engineered tissues is still a major challenge …