Applications of serine integrases in synthetic biology over the past decade
Serine integrases are emerging as one of the most powerful biological tools for
biotechnology. Over the past decade, many research papers have been published on the …
biotechnology. Over the past decade, many research papers have been published on the …
Chromosomal integrons are genetically and functionally isolated units of genomes
P Blanco, F Trigo da Roza… - Nucleic Acids …, 2024 - academic.oup.com
Integrons are genetic elements that increase the evolvability of bacteria by capturing new
genes and stockpiling them in arrays. Sedentary chromosomal integrons (SCIs) can be …
genes and stockpiling them in arrays. Sedentary chromosomal integrons (SCIs) can be …
Overcoming the Challenges of Megabase-Sized Plasmid Construction in Escherichia coli
Although Escherichia coli has been a popular tool for plasmid construction, this bacterium
was believed to be “unsuitable” for constructing a large plasmid whose size exceeds 500 …
was believed to be “unsuitable” for constructing a large plasmid whose size exceeds 500 …
Rational construction of a high-quality and high-efficiency biosynthetic system and fermentation optimization for A82846B based on combinatorial strategies in …
X Zhao, C Zhu, W Gao, H Xie, Z Lyu, Q Zhao… - Microbial Cell Factories, 2024 - Springer
Background Oritavancin is a new generation of semi-synthetic glycopeptide antibiotics
against Gram-positive bacteria, which served as the first and only antibiotic with a single …
against Gram-positive bacteria, which served as the first and only antibiotic with a single …
HK022 bacteriophage Integrase mediated RMCE as a potential tool for human gene therapy
A Elias, H Kassis, SA Elkader, N Gritsenko… - Nucleic acids …, 2020 - academic.oup.com
HK022 coliphage site-specific recombinase Integrase (Int) can catalyze integrative site-
specific recombination and recombinase-mediated cassette exchange (RMCE) reactions in …
specific recombination and recombinase-mediated cassette exchange (RMCE) reactions in …
[图书][B] Isolation, Characterization, and Annotation of a Novel Mycobacteriophage Eaglepride
U Sahi - 2022 - search.proquest.com
Bacteriophages (phages) are obligate intracellular parasitic viruses that infect bacterial host
cells. They are the most abundant biological entity on the planet, with an estimated 1031 …
cells. They are the most abundant biological entity on the planet, with an estimated 1031 …
Genetic drivers of chromosomal integron stability
The integron is a bacterial recombination system that allows acquisition, stockpiling and
expression of promoterless genes embedded in cassettes. Some integrons, like the one …
expression of promoterless genes embedded in cassettes. Some integrons, like the one …