Pathogen-derived extracellular vesicle-associated molecules that affect the host immune system: an overview

ME Kuipers, CH Hokke, HH Smits… - Frontiers in …, 2018 - frontiersin.org
Recently, the interest in extracellular vesicles (EVs) released by pathogens like bacteria,
fungi, and parasites has rapidly increased. Many of these pathogens actively modulate the …

Potential roles of fungal extracellular vesicles during infection

LS Joffe, L Nimrichter, ML Rodrigues, M Del Poeta - MSphere, 2016 - Am Soc Microbiol
Extracellular vesicles (EVs) are produced by virtually all cell types. Within the past few years,
work in this field has revealed more information about fungal EVs. Fungal EVs have been …

The viscoelastic properties of the fungal cell wall allow traffic of AmBisome as intact liposome vesicles

L Walker, P Sood, MD Lenardon, G Milne, J Olson… - MBio, 2018 - Am Soc Microbiol
The fungal cell wall is a critically important structure that represents a permeability barrier
and protective shield. We probed Candida albicans and Cryptococcus neoformans with …

Cryptococcus extracellular vesicles properties and their use as vaccine platforms

J Rizzo, SSW Wong, AD Gazi… - Journal of …, 2021 - Wiley Online Library
Whereas extracellular vesicle (EV) research has become commonplace in different
biomedical fields, this field of research is still in its infancy in mycology. Here we provide a …

Comparative molecular and immunoregulatory analysis of extracellular vesicles from Candida albicans and Candida auris

D Zamith-Miranda, HM Heyman, SP Couvillion… - Msystems, 2021 - Am Soc Microbiol
Candida auris is a recently described multidrug-resistant pathogenic fungus that is
increasingly responsible for health care-associated outbreaks across the world …

Media matters! Alterations in the loading and release of Histoplasma capsulatum extracellular vesicles in response to different nutritional milieus

LG Cleare, D Zamith, HM Heyman… - Cellular …, 2020 - Wiley Online Library
Histoplasma capsulatum is a dimorphic fungus that most frequently causes pneumonia, but
can also disseminate and proliferate in diverse tissues. Histoplasma capsulatum has a …

Extracellular nanovesicles released from the commensal yeast Malassezia sympodialis are enriched in allergens and interact with cells in human skin

HJ Johansson, H Vallhov, T Holm, U Gehrmann… - Scientific reports, 2018 - nature.com
Malassezia sympodialis is a dominant commensal fungi in the human skin mycobiome but is
also associated with common skin disorders including atopic eczema (AE). M. sympodialis …

A novel protocol for the isolation of fungal extracellular vesicles reveals the participation of a putative scramblase in polysaccharide export and capsule construction in …

FCG Reis, BS Borges, LJ Jozefowicz, BAG Sena… - MSphere, 2019 - Am Soc Microbiol
Regular protocols for the isolation of fungal extracellular vesicles (EVs) are time-consuming,
hard to reproduce, and produce low yields. In an attempt to improve the protocols used for …

Extracellular vesicle-associated transitory cell wall components and their impact on the interaction of fungi with host cells

L Nimrichter, MM De Souza, M Del Poeta… - Frontiers in …, 2016 - frontiersin.org
Classic cell wall components of fungi comprise the polysaccharides glucans and chitin, in
association with glycoproteins and pigments. During the last decade, however, system …

Regulation of the fungal secretome

SW McCotter, LC Horianopoulos, JW Kronstad - Current genetics, 2016 - Springer
The ability of countless representatives of the Kingdom Fungi to adapt to and proliferate in
diverse environments is facilitated by regulation of their secretomes to respond to changes …