Oximes have been studied for decades because of their significant roles as
acetylcholinesterase reactivators. Over the last twenty years, a large number of oximes have …

Insulin resistance contributes to metabolic disorders in obesity and type 2 diabetes. In
mechanisms of insulin resistance, the roles of glucose, fatty acids, and amino acids have …

Oxidative stress resulting from the depletion of glutathione (GSH) level plays a vital role in
generating various degenerative diseases, including type 2 diabetes (T2D). We tested the …

Abstract Aims Imidazo [1, 2-a] pyridine-based analogues have recently gained significant
interest because of their wide spectrum of biological activities including anti-cancer …

Type 2 diabetes has been a global health challenge over the decades and is among the
leading causes of death. Several treatment approaches have been developed, but more …

The protozoan Leishmania donovani, from trypanosomatids family is a deadly human
pathogen responsible for causing Visceral Leishmaniasis. Unavailability of proper treatment …

Insulin resistance (IR) is the key pathophysiological cause of type 2 diabetes, and
inflammation has been implicated in it. The death domain (DD) of the adaptor protein …

The world today, although, has developed an elaborate health system to fortify against
known and unknown diseases, it continues to be challenged by new as well as emerging …

One of the primary problems arising worldwide is the increasing risk of parasitic disease in
the developing countries. In that list, the neglected tropical diseases have been affecting the …

Adenanthera pavonina is a medicinal plant with numerous potential secondary metabolites
showing a significant level of antidiabetic activity. The objective of the current study was to …