Pneumonia in the developing world: C haracteristic features and approach to management

SJ Aston - Respirology, 2017 - Wiley Online Library
Community‐acquired pneumonia (CAP) is a common cause of morbidity and mortality in
adults worldwide, but its epidemiology varies markedly by region. Whilst in high‐income …

[HTML][HTML] Pneumocystis jirovecii pneumonia in developing countries

YDA Rodríguez, G Wissmann, AL Müller… - Parasite: journal de la …, 2011 - ncbi.nlm.nih.gov
Pneumocystis pneumonia (PcP) is a serious fungal infection among immunocompromised
patients. In developed countries, the epidemiology and clinical spectrum of PcP have been …

Etiology and Incidence of viral and bacterial acute respiratory illness among older children and adults in rural western Kenya, 2007–2010

DR Feikin, MK Njenga, G Bigogo, B Aura, G Aol, A Audi… - 2012 - journals.plos.org
Background Few comprehensive data exist on disease incidence for specific etiologies of
acute respiratory illness (ARI) in older children and adults in Africa. Methodology/Principal …

Etiology and risk factors for mortality in an adult community-acquired pneumonia cohort in Malawi

SJ Aston, A Ho, H Jary, J Huwa, T Mitchell… - American journal of …, 2019 - atsjournals.org
Rationale: In the context of rapid antiretroviral therapy rollout and an increasing burden of
noncommunicable diseases, there are few contemporary data describing the etiology and …

[HTML][HTML] Community-acquired pneumonia and tuberculosis: differential diagnosis and the use of fluoroquinolones

RF Grossman, PR Hsueh, SH Gillespie… - International Journal of …, 2014 - Elsevier
The respiratory fluoroquinolones moxifloxacin, gemifloxacin, and high-dose levofloxacin are
recommended in guidelines for effective empirical antimicrobial therapy of community …

The prevalence of laboratory-confirmed Pneumocystis jirovecii in HIV-infected adults in Africa: A systematic review and meta-analysis

NK Wills, DS Lawrence, E Botsile… - Medical …, 2021 - academic.oup.com
Abstract Background: The epidemiology of Pneumocystis jirovecii, known to colonize the
respiratory tract and cause a life-threatening HIV-associated pneumonia (PCP), is poorly …

Diagnosis of COVID-19: considerations, controversies and challenges in South Africa

K Dheda, S Jaumdally, M Davids, JW Chang… - Wits Journal of Clinical …, 2020 - journals.co.za
Coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome
coronavirus 2 is a global pandemic that has resulted in over 1.5 million confirmed cases and …

Integrating sepsis management recommendations into clinical care guidelines for district hospitals in resource-limited settings: the necessity to augment new …

ST Jacob, M Lim, P Banura, S Bhagwanjee, J Bion… - BMC medicine, 2013 - Springer
Several factors contribute to the high mortality attributed to severe infections in resource-
limited settings. While improvements in survival and processes of care have been made in …

Community-acquired pneumonia in sub-Saharan Africa

SJ Aston, J Rylance - Seminars in respiratory and critical care …, 2016 - thieme-connect.com
Community-acquired pneumonia (CAP) in sub-Saharan Africa is a common cause of adult
hospitalization and is associated with significant mortality. Human immunodeficiency virus …

Low Prevalence of Pneumocystis pneumonia (PCP) but High Prevalence of Pneumocystis dihydropteroate synthase (dhps) Gene Mutations in HIV-Infected Persons …

SM Taylor, SR Meshnick, W Worodria, A Andama… - PLoS …, 2012 - journals.plos.org
Pneumocystis jirovecii pneumonia (PCP) is an important opportunistic infection in patients
infected with HIV, but its burden is incompletely characterized in those areas of sub-Saharan …