Cognitive dysfunction is a common, often long-term complaint following acquired traumatic
brain injury (TBI). Cognitive deficits suggest dysfunction in hippocampal circuits. The goal of …

The precise function of specialized GABAergic interneuron subtypes is required to provide
appropriate synaptic inhibition for regulating principal neuron excitability and …

Cognitive impairment is a common symptom after traumatic brain injury (TBI). Memory, in
particular, is often disrupted during chronic post-injury recovery. To understand the sex …

Neonatal hypoxic-ischemic (HI) injury leads to deficits in hippocampal parvalbumin (PV)+
interneurons (INs) and working memory. Therapeutic hypothermia (TH) does not prevent …

Mild traumatic brain injury (mTBI) gives rise to a remarkable breadth of pathobiological
consequences, principal among which are traumatic axonal injury and perturbation of the …

Concussion, caused by a rotational acceleration/deceleration injury mild enough to avoid
structural brain damage, is insufficiently captured in recent preclinical models, hampering …

Traumatic brain injury (TBI) is a leading cause of mortality and is associated with a high rate
of functional comorbidities, including motor, cognitive, anxiety, depression, and emotional …

Pathological impairments in the regulation of affect (ie, emotion) and flexible decision-
making are commonly observed across numerous neuropsychiatric disorders and are …

Traumatic brain injury (TBI) affects millions of people annually, and most cases are classified
as mild TBI (mTBI). Ketamine is a potent trauma analgesic and anesthetic with anti …

Preclinical investigations into neuroprotective agents for traumatic brain injury (TBI) have
shown promise when administered before or very early after experimental TBI. However …