Susceptibility-weighted imaging (SWI) evolved from simple two-dimensional T2*-weighted
sequences to three-dimensional sequences with improved spatial resolution and enhanced …

Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In
the past decade, development of the new magnetic resonance imaging technique …

Quantitative susceptibility mapping (QSM) has enabled magnetic resonance imaging (MRI)
of tissue magnetic susceptibility to advance from simple qualitative detection of hypointense …

Parkinson disease is characterized by dopaminergic cell loss in the substantia nigra of the
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …

The differential diagnosis of parkinsonian syndromes is considered one of the most
challenging in neurology and error rates in the clinical diagnosis can be high even at …

Background Quantitative susceptibility mapping (QSM) and R2* relaxation rate mapping
have demonstrated increased iron deposition in the substantia nigra of patients with …

Background Microstructural changes in deep gray matter (DGM) nuclei are related to
physiological behavior, cognition, and memory. Therefore, it is critical to study age …

Parkinson's disease (PD) is a neurodegenerative synucleinopathy characterized by the
degeneration of neuromelanin (NM)-containing dopaminergic neurons and deposition of …

Quantitative susceptibility mapping (QSM) is an MR technique that depicts and quantifies
magnetic susceptibility sources. Mapping iron, the dominant susceptibility source in the …

Quantitative susceptibility mapping (QSM) has gained broad interest in the field by extracting
bulk tissue magnetic susceptibility, predominantly determined by myelin, iron and calcium …