Metabolic engineering in the host Yarrowia lipolytica

AM Abdel-Mawgoud, KA Markham, CM Palmer… - Metabolic …, 2018 - Elsevier
The nonconventional, oleaginous yeast, Yarrowia lipolytica is rapidly emerging as a
valuable host for the production of a variety of both lipid and nonlipid chemical products …

[HTML][HTML] Synthetic biology tools for engineering Yarrowia lipolytica

M Larroudé, T Rossignol, JM Nicaud… - Biotechnology …, 2018 - Elsevier
The non-conventional oleaginous yeast Yarrowia lipolytica shows great industrial promise. It
naturally produces certain compounds of interest but can also artificially generate non-native …

Standardized Markerless Gene Integration for Pathway Engineering in Yarrowia lipolytica

C Schwartz, M Shabbir-Hussain, K Frogue… - ACS synthetic …, 2017 - ACS Publications
The yeast Yarrowia lipolytica is a promising microbial host due to its native capacity to
produce lipid-based chemicals. Engineering stable production strains requires genomic …

Advances in promoter engineering: novel applications and predefined transcriptional control

AP Cazier, J Blazeck - Biotechnology Journal, 2021 - Wiley Online Library
Synthetic biology continues to progress by relying on more robust tools for transcriptional
control, of which promoters are the most fundamental component. Numerous studies have …

Advancing Yarrowia lipolytica as a superior biomanufacturing platform by tuning gene expression using promoter engineering

ML Sun, TQ Shi, L Lin, R Ledesma-Amaro, XJ Ji - Bioresource Technology, 2022 - Elsevier
Yarrowia lipolytica is recognized as an excellent non-conventional yeast in the field of
biomanufacturing, where it is used as a host to produce oleochemicals, terpenes, organic …

Synthetic biology, systems biology, and metabolic engineering of Yarrowia lipolytica toward a sustainable biorefinery platform

J Ma, Y Gu, M Marsafari, P Xu - … : Official Journal of the Society for …, 2020 - academic.oup.com
Yarrowia lipolytica is an oleaginous yeast that has been substantially engineered for
production of oleochemicals and drop-in transportation fuels. The unique acetyl …

Advances in synthetic biology tools paving the way for the biomanufacturing of unusual fatty acids using the Yarrowia lipolytica chassis

K Wang, TQ Shi, L Lin, P Wei, R Ledesma-Amaro… - Biotechnology …, 2022 - Elsevier
Unusual fatty acids with special carbon chain length or functional groups have been
extensively used in the chemical, material, nutraceutical, and pharmaceutical industries. The …

Promoter Architecture and Promoter Engineering in Saccharomyces cerevisiae

H Tang, Y Wu, J Deng, N Chen, Z Zheng, Y Wei, X Luo… - Metabolites, 2020 - mdpi.com
Promoters play an essential role in the regulation of gene expression for fine-tuning genetic
circuits and metabolic pathways in Saccharomyces cerevisiae (S. cerevisiae). However …

Synthetic biology expands the industrial potential of Yarrowia lipolytica

KA Markham, HS Alper - Trends in biotechnology, 2018 - cell.com
The oleaginous yeast Yarrowia lipolytica is quickly emerging as the most popular non-
conventional (ie, non-model organism) yeast in the bioproduction field. With a high …

Metabolic Engineering of Yarrowia lipolytica for Terpenoid Production: Tools and Strategies

TL Zhang, HW Yu, LD Ye - ACS Synthetic Biology, 2023 - ACS Publications
Terpenoids are a diverse group of compounds with isoprene units as basic building blocks.
They are widely used in the food, feed, pharmaceutical, and cosmetic industries due to their …