Poly (propylene imine) dendrimer as an emerging polymeric nanocarrier for anticancer drug and gene delivery
V Singh, A Sahebkar, P Kesharwani - European Polymer Journal, 2021 - Elsevier
Dendrimers are well-defined globular macromolecules with multiple polymeric branching
that are amenable to undergo structural modifications. This property makes dendrimers …
that are amenable to undergo structural modifications. This property makes dendrimers …
Dendrimer as a promising nanocarrier for the delivery of doxorubicin as an anticancer therapeutics
V Singh, P Kesharwani - Journal of Biomaterials Science, Polymer …, 2021 - Taylor & Francis
Dendrimers are macromolecules with high-polymeric branching capable of undergoing
major modifications. These characteristics make them an efficient nanocarrier capable of …
major modifications. These characteristics make them an efficient nanocarrier capable of …
Systematically designed chitosan-coated solid lipid nanoparticles of ferulic acid for effective management of Alzheimer's disease: A preclinical evidence
Ferulic acid (FA) is a ubiquitous natural plant bioactive with distinctive promise in
neurodegenerative disorders. However, its therapeutic efficacy gets compromised owing to …
neurodegenerative disorders. However, its therapeutic efficacy gets compromised owing to …
Introduction to quality by design (QbD): fundamentals, principles, and applications
Pharmaceutical quality has been under long debate for decades. In the current scenario of
regulatory environments, the pharmaceutical industry is continuously facing challenges with …
regulatory environments, the pharmaceutical industry is continuously facing challenges with …
The recent progress in modification of polymeric membranes using organic macromolecules for water treatment
For decades, the water deficit has been a severe global issue. A reliable supply of water is
needed to ensure sustainable economic development in population growth, industrialization …
needed to ensure sustainable economic development in population growth, industrialization …
QbD-steered development of biotin-conjugated nanostructured lipid carriers for oral delivery of chrysin: role of surface modification for improving biopharmaceutical …
Bioactives are documented to exhibit diverse pharmacological activities, however, their low
and inconsistent bioavailability primarily pose serious impediment against their potential …
and inconsistent bioavailability primarily pose serious impediment against their potential …
Application of chemometric approach for QbD-enabled development and validation of an RP-HPLC method for estimation of methotrexate
The present work describes Quality by design (QbD)-oriented development of a reverse
phase high performance liquid chromatographic (RP-HPLC) method for quantification of …
phase high performance liquid chromatographic (RP-HPLC) method for quantification of …
Systematic development of drug nanocargos using formulation by design (FbD): an updated overview
Nanostructured drug delivery formulations have lately gained enormous attention,
contributing to their systematic development. Issuance of quality by design (QbD) guidelines …
contributing to their systematic development. Issuance of quality by design (QbD) guidelines …
Raloxifene-loaded SLNs with enhanced biopharmaceutical potential: QbD-steered development, in vitro evaluation, in vivo pharmacokinetics, and IVIVC
Raloxifene hydrochloride, a second-generation selective estrogen receptor modulator, has
been approved for the management of breast cancer. However, it is known to exhibit poor …
been approved for the management of breast cancer. However, it is known to exhibit poor …