Cytokines in inflammatory disease
This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines.
Numerous studies have implicated that inflammatory cytokines exert important effects with …
Numerous studies have implicated that inflammatory cytokines exert important effects with …
Apoptosis, autophagy, NETosis, necroptosis, and pyroptosis mediated programmed cell death as targets for innovative therapy in rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease that can lead to clinical
manifestations of systemic diseases. Its leading features include chronic synovial …
manifestations of systemic diseases. Its leading features include chronic synovial …
Age and age-related diseases: role of inflammation triggers and cytokines
IM Rea, DS Gibson, V McGilligan… - Frontiers in …, 2018 - frontiersin.org
Cytokine dysregulation is believed to play a key role in the remodeling of the immune
system at older age, with evidence pointing to an inability to fine-control systemic …
system at older age, with evidence pointing to an inability to fine-control systemic …
[HTML][HTML] Role of the NLRP3 inflammasome in autoimmune diseases
Z Li, J Guo, L Bi - Biomedicine & pharmacotherapy, 2020 - Elsevier
NOD-like receptor family pyrin domain containing 3 (NLRP3) is an intracellular receptor that
senses foreign pathogens and endogenous danger signals. It assembles with apoptosis …
senses foreign pathogens and endogenous danger signals. It assembles with apoptosis …
Focus on the Role of NLRP3 Inflammasome in Diseases
R Fusco, R Siracusa, T Genovese… - International journal of …, 2020 - mdpi.com
Inflammation is a protective reaction activated in response to detrimental stimuli, such as
dead cells, irritants or pathogens, by the evolutionarily conserved immune system and is …
dead cells, irritants or pathogens, by the evolutionarily conserved immune system and is …
Crosstalk between gut microbiota and innate immunity and its implication in autoimmune diseases
The emerging concept of microbiota contributing to local mucosal homeostasis has fueled
investigation into its specific role in immunology. Gut microbiota is mostly responsible for …
investigation into its specific role in immunology. Gut microbiota is mostly responsible for …
[HTML][HTML] Innate immunity drives pathogenesis of rheumatoid arthritis
MI Edilova, A Akram, AA Abdul-Sater - Biomedical Journal, 2021 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disease affecting∼ 1% of the general
population. This disease is characterized by persistent articular inflammation and joint …
population. This disease is characterized by persistent articular inflammation and joint …
NLRP3 inflammasome: checkpoint connecting innate and adaptive immunity in autoimmune diseases
Y Zhang, W Yang, W Li, Y Zhao - Frontiers in immunology, 2021 - frontiersin.org
Autoimmune diseases are a broad spectrum of human diseases that are characterized by
the breakdown of immune tolerance and the production of autoantibodies. Recently …
the breakdown of immune tolerance and the production of autoantibodies. Recently …
The role of inflammasomes in human diseases and their potential as therapeutic targets
J Yao, K Sterling, Z Wang, Y Zhang… - Signal Transduction and …, 2024 - nature.com
Inflammasomes are large protein complexes that play a major role in sensing inflammatory
signals and triggering the innate immune response. Each inflammasome complex has three …
signals and triggering the innate immune response. Each inflammasome complex has three …
NLRP3 inflammasome activation contributes to the pathogenesis of rheumatoid arthritis
C Guo, R Fu, S Wang, Y Huang, X Li… - Clinical & …, 2018 - academic.oup.com
Nucleotide-binding, oligomerization domain (NOD)-like receptor family, pyrin domain
containing 3 (NLRP3) gene polymorphism was reported to be associated with susceptibility …
containing 3 (NLRP3) gene polymorphism was reported to be associated with susceptibility …