Establishing a substrate-assisted mechanism for the pre-transfer editing in SerRS and IleRS: A QM/QM investigation

MM Aboelnga, JW Gauld - Structural Chemistry, 2024 - Springer
Aminoacyl-tRNA synthetases (aaRS) are key enzymes in protein biosynthesis that employ
various editing mechanisms to ensure faithful translation of genetic information. Seryl-tRNA …
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Effect of oriented external electric fields on the Staudinger [2+ 2] cycloaddition reaction: a computational study

O Alvarado, M Alvarado, FE Medina… - Theoretical Chemistry …, 2025 - Springer
Abstract The Staudinger ketene-imine [2+ 2] cycloaddition provides an efficient strategy to
produce polysubstituted β-lactam rings, resulting in two pairs of enantiomers with cis/trans …
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