Background: Despite significant advancement in oncology research, cancer still poses one
of the leading causes of mortality worldwide. The increased incidences of cancer may be …

Covering: 2007. Previous review: Nat. Prod. Rep., 2008, 25, 35This review covers the
literature published in 2007 for marine natural products, with 948 citations (627 for the …

Macrolides are a diverse class of hydrophobic compounds characterized by a macrocyclic
lactone ring and distinguished by variable side chains/groups. Some of the most well …

Covering: up to the end of February 2017 Nudibranchs have attracted the attention of natural
product researchers due to the potential for discovery of bioactive metabolites, in …

Numerous studies have assembled a complex picture, in which extracellular stimuli and
intracellular signaling pathways modulate the chondrocyte phenotype. Because many …

The natural products of heterobranch molluscs display a huge variability both in structure
and in their bioactivity. Despite the considerable lack of information, it can be observed from …

The chemical investigation of marine mollusks has led to the isolation of a wide variety of
bioactive metabolites, which evolved in marine organisms as favorable adaptations to …

Aplyronine A (ApA) is a marine natural product that shows potent antitumor activity. While
both ApA and ApC, a derivative of ApA that lacks a trimethylserine ester moiety, inhibit actin …

This review with 387 references covers the literature until the end of November 2013 on the
synthesis of multiply arylated heteroarenes via highly selective palladium-catalyzed direct C …

Covering: up to 2014 Various marine natural products that target cytoskeletal proteins have
been discovered. A few of these compounds have recently been shown to induce or inhibit …