Leveraging diet to engineer the gut microbiome

M Wolter, ET Grant, M Boudaud, A Steimle… - Nature reviews …, 2021 - nature.com
Autoimmune diseases, including inflammatory bowel disease, multiple sclerosis and
rheumatoid arthritis, have distinct clinical presentations but share underlying patterns of gut …

Current sampling methods for gut microbiota: a call for more precise devices

Q Tang, G Jin, G Wang, T Liu, X Liu… - Frontiers in cellular and …, 2020 - frontiersin.org
The development of next-generation sequencing technology has enabled researchers to
explore and understand the gut microbiome from a broader and deeper perspective …

[HTML][HTML] Design, construction, and in vivo augmentation of a complex gut microbiome

AG Cheng, PY Ho, A Aranda-Díaz, S Jain, BY Feiqiao… - Cell, 2022 - cell.com
Efforts to model the human gut microbiome in mice have led to important insights into the
mechanisms of host-microbe interactions. However, the model communities studied to date …

Bifidobacterium infantis treatment promotes weight gain in Bangladeshi infants with severe acute malnutrition

MJ Barratt, S Nuzhat, K Ahsan, SA Frese… - Science Translational …, 2022 - science.org
Disrupted development of the gut microbiota is a contributing cause of childhood
malnutrition. Bifidobacterium longum subspecies infantis is a prominent early colonizer of …

Mobile genetic elements from the maternal microbiome shape infant gut microbial assembly and metabolism

T Vatanen, KS Jabbar, T Ruohtula, J Honkanen… - Cell, 2022 - cell.com
The perinatal period represents a critical window for cognitive and immune system
development, promoted by maternal and infant gut microbiomes and their metabolites. Here …

Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease

JM Pickard, MY Zeng, R Caruso… - Immunological …, 2017 - Wiley Online Library
The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …

A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility

MS Desai, AM Seekatz, NM Koropatkin, N Kamada… - Cell, 2016 - cell.com
Despite the accepted health benefits of consuming dietary fiber, little is known about the
mechanisms by which fiber deprivation impacts the gut microbiota and alters disease risk …

[HTML][HTML] Bacteroides utilization for dietary polysaccharides and their beneficial effects on gut health

J Cheng, J Hu, F Geng, S Nie - Food Science and Human Wellness, 2022 - Elsevier
Polysaccharide was a class of macromolecular substance with various bioactive functions.
Gut symbiotic microorganisms could utilize the polysaccharides from various sources, thus …

Effects of microbiota-directed foods in gnotobiotic animals and undernourished children

JL Gehrig, S Venkatesh, HW Chang, MC Hibberd… - Science, 2019 - science.org
INTRODUCTION There is a dimension to postnatal human development that involves
assembly of microbial communities in different body habitats, including the gut. Children with …

Generation of genome-scale metabolic reconstructions for 773 members of the human gut microbiota

S Magnúsdóttir, A Heinken, L Kutt, DA Ravcheev… - Nature …, 2017 - nature.com
Genome-scale metabolic models derived from human gut metagenomic data can be used
as a framework to elucidate how microbial communities modulate human metabolism and …