Secondary radiation emission induced by nuclear reactions is correlated to the path of ions
in matter. Therefore, such penetrating radiation can be used for in vivo control of …

In-vivo range verification has been a hot topic in particle therapy for about two decades. In
spite of vast efforts made by research groups all over the world, clinical devices and …

We present a full-scale clinical prototype system for in vivo range verification of proton pencil-
beams using the prompt gamma-ray spectroscopy method. The detection system consists of …

In proton therapy, patients benefit from the precise deposition of the dose in the tumor
volume due to the interaction of charged particles with matter. Currently, the determination of …

Owing to the favorable physical and biological properties of swift ions in matter, their
application to radiation therapy for highly selective cancer treatment is rapidly spreading …

We recently proposed a new approach for the real-time monitoring of particle therapy
treatments with the goal of achieving high sensitivities on the particle range measurement …

A feasibility study on the imaging of monochromatic carbon-ion beams for carbon-ion
therapy was performed. The evaluation was based on Monte Carlo simulations and beam …

We propose a novel prompt-gamma (PG) imaging modality for real-time monitoring in proton
therapy: PG time imaging (PGTI). By measuring the time-of-flight (TOF) between a beam …

Objective. Lutetium–yttrium orthosilicate (LYSO)-based Compton camera (CC) has been
proposed for prompt gamma imaging due to its high detection efficiency and position …

The applicability extent of hadron therapy for tumor treatment is currently limited by the lack
of reliable online monitoring techniques. An active topic of investigation is the research of …