Interplay between inflammation and thrombosis in cardiovascular pathology

K Stark, S Massberg - Nature Reviews Cardiology, 2021 - nature.com
Thrombosis is the most feared complication of cardiovascular diseases and a main cause of
death worldwide, making it a major health-care challenge. Platelets and the coagulation …

Rheumatoid arthritis-interstitial lung disease: manifestations and current concepts in pathogenesis and management

S Kadura, G Raghu - European Respiratory Review, 2021 - Eur Respiratory Soc
Rheumatoid arthritis (RA) is a systemic inflammatory disorder, with the most common extra-
articular manifestation of RA being lung involvement. While essentially any of the lung …

Filgotinib versus placebo or adalimumab in patients with rheumatoid arthritis and inadequate response to methotrexate: a phase III randomised clinical trial

B Combe, A Kivitz, Y Tanaka… - Annals of the …, 2021 - ard.bmj.com
Objective To evaluate the efficacy and safety of the Janus kinase-1-preferential inhibitor
filgotinib versus placebo or tumour necrosis factor-α inhibitor therapy in patients with active …

Alopecia areata: disease characteristics, clinical evaluation, and new perspectives on pathogenesis

LC Strazzulla, EHC Wang, L Avila, KL Sicco… - Journal of the American …, 2018 - Elsevier
Alopecia areata (AA) is a common, inflammatory, nonscarring type of hair loss. Significant
variations in the clinical presentation of AA have been observed, ranging from small, well …

2015 American College of Rheumatology guideline for the treatment of rheumatoid arthritis

JA Singh, KG Saag, SL Bridges Jr, EA Akl… - Arthritis & …, 2016 - Wiley Online Library
Objective To develop a new evidence‐based, pharmacologic treatment guideline for
rheumatoid arthritis (RA). Methods We conducted systematic reviews to synthesize the …

Cardiovascular risk in inflammatory arthritis: rheumatoid arthritis and gout

R Hansildaar, D Vedder, M Baniaamam… - The Lancet …, 2021 - thelancet.com
The increased risk of cardiovascular morbidity and mortality in rheumatoid arthritis and gout
has been increasingly acknowledged in past decades, with accumulating evidence that …

Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease

L Liberale, F Montecucco, JC Tardif… - European heart …, 2020 - academic.oup.com
The ongoing worldwide increase in life expectancy portends a rising prevalence of age-
related cardiovascular (CV) diseases in the coming decades that demands a deeper …

A novel drug combination of mangiferin and cinnamic acid alleviates rheumatoid arthritis by inhibiting TLR4/NFκB/NLRP3 activation-induced pyroptosis

W Li, K Wang, Y Liu, H Wu, Y He, C Li, Q Wang… - Frontiers in …, 2022 - frontiersin.org
Growing evidence shows that Baihu-Guizhi decoction (BHGZD), a traditional Chinese
medicine (TCM)-originated disease-modifying anti-rheumatic prescription, may exert a …

Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications

BR England, GM Thiele, DR Anderson, TR Mikuls - Bmj, 2018 - bmj.com
Rheumatoid arthritis is a systemic autoimmune disease characterized by excess morbidity
and mortality from cardiovascular disease. Mechanisms linking rheumatoid arthritis and …

Malignancy risk with tofacitinib versus TNF inhibitors in rheumatoid arthritis: results from the open-label, randomised controlled ORAL Surveillance trial

JR Curtis, K Yamaoka, YH Chen, DL Bhatt… - Annals of The …, 2023 - ard.bmj.com
Objectives To evaluate malignancies and their associations with baseline risk factors and
cardiovascular risk scores with tofacitinib versus tumour necrosis factor inhibitors (TNFi) in …