Natural products represents an important source of new lead compounds in drug discovery
research. Several drugs currently used as therapeutic agents have been developed from …

Nature has abundant source of drugs that need to be identified/purified for use as essential
biologics, either individually or in combination in the modern medical field. These drugs are …

Chemodynamic therapy (CDT) is an emerging endogenous stimulation activated tumor
treatment approach that exploiting iron-containing nanomedicine as catalyst to convert …

Chitosan displays a dual function, acting as both an active ingredient and/or carrier for
pharmaceutical bioactive molecules and metal ions. Its hydroxyl-and amino-reactive groups …

Abstract β-Lapachone (β-lap, 1), an ortho-naphthoquinone natural product isolated from the
lapacho tree (Tabebuia avellanedae) in many regions of South America, has received …

In spite of substantial progress made toward understanding cancer pathogenesis, this
disease remains one of the leading causes of mortality. Thus, there is an urgent need to …

Head and neck cancer is a highly genetic and metabolic heterogeneous collection of
malignancies of the lip, oral cavity, salivary glands, pharynx, esophagus, paranasal sinuses …

Abstract β-Lapachone is an ortho-naphthoquinone originally isolated from the heartwood of
Handroanthus impetiginosus and can be obtained through synthesis from lapachol …

Despite ortho-quinones showing several biological and pharmacological activities, there is
still a lack of biophysical characterization of their interaction with albumin-the main carrier of …

One of the primary diseases that cause death worldwide is cancer. Cancer cells can be
intrinsically resistant or acquire resistance to therapies and drugs used for cancer treatment …