This paper focuses on the predictive model development for a pharmaceutically relevant
model granulation process. A population balance modeling (PBM) framework has been …

Abstract Model-driven design approaches have great potential to improve current
engineering workflows for wet granulation and other particulate processes. The key to model …

The preparation of pellets using a high-shear granulator in a rapid single-step is considered
a good economic alternative to the extrusion spheronization process. As process …

A quantitative analysis of variations in granule microstructure based upon changes in
primary particle size and bed preparation is presented. The granule microstructures are …

Nucleation is an important wet granulation rate process that sometimes has a profound
effect on granule attributes and which needs to be captured in process modelling studies …

The major focus of this study, the second part of a series, is to simulate the net granulation
process of TiO 2 powder using 1-D discretized population balance modelling (PBM) and …

In the literature there are some publications about the effect of impeller and chopper speeds
on product parameters. However, there is no information about the effect of temperature …

This paper, the second of a series, analyzes the effect of binder amount on the kinetics of
wet granulation process. Granulation experiments were conducted in batch, lab-scale high …

Sažetak Ovim istraživanjem sagledano je mokro granuliranje mikrokristalne celuloze u
fluidiziranom sloju s raspršivanjem kao nužan procesni korak u osiguravanju željene …

Sažetak U ovome radu sagledano je mokro granuliranje prevrtanjem kao moguća procesna
tehnologija za pripravu pogodne formulacije agrikulturne tvari Agrocal® za poboljšanje …