Hypoxia inducible factor as a therapeutic target for atherosclerosis
T Jain, EA Nikolopoulou, Q Xu, A Qu - Pharmacology & therapeutics, 2018 - Elsevier
Atherosclerosis is a highly prevalent disease that can significantly increase the risk of major
vascular events, such as myocardial or cerebral infarctions. The anoxemia theory states that …
vascular events, such as myocardial or cerebral infarctions. The anoxemia theory states that …
[HTML][HTML] The role and therapeutic potential of nuclear factor κB (NF-κB) in ischemic stroke
G Xu, F Dong, L Su, ZX Tan, M Lei, L Li, D Wen… - Biomedicine & …, 2024 - Elsevier
Stroke is a prevalent cerebrovascular condition with a global impact, causing significant
rates of illness and death. Despite extensive research, the available treatment options for …
rates of illness and death. Despite extensive research, the available treatment options for …
Vascular changes and hypoxia in periodontal disease as a link to systemic complications
D Celik, A Kantarci - Pathogens, 2021 - mdpi.com
The hypoxic microenvironment caused by oral pathogens is the most important cause of the
disruption of dynamic hemostasis between the oral microbiome and the immune system …
disruption of dynamic hemostasis between the oral microbiome and the immune system …
Mitochondrial metabolism as target of the neuroprotective role of erythropoietin in Parkinson's disease
F Rey, S Ottolenghi, T Giallongo, A Balsari, C Martinelli… - Antioxidants, 2021 - mdpi.com
Existing therapies for Parkinson's disease (PD) are only symptomatic. As erythropoietin
(EPO) is emerging for its benefits in neurodegenerative diseases, here, we test the …
(EPO) is emerging for its benefits in neurodegenerative diseases, here, we test the …
3D bioprinting of novel biocompatible scaffolds for endothelial cell repair
The aim of this study was to develop and evaluate an optimized 3D bioprinting technology in
order to fabricate novel scaffolds for the application of endothelial cell repair. Various …
order to fabricate novel scaffolds for the application of endothelial cell repair. Various …
Flow Mediated Skin Fluorescence technique reveals remarkable effect of age on microcirculation and metabolic regulation in type 1 diabetes
J Katarzynska, A Borkowska, P Czajkowski, A Los… - Microvascular …, 2019 - Elsevier
Abstract Study description Flow Mediated Skin Fluorescence (FMSF) is a novel technique for
non-invasive evaluation of the microcirculation and metabolic regulation. This study …
non-invasive evaluation of the microcirculation and metabolic regulation. This study …
Can erythropoietin reduce hypoxemic neurological damages in neonates with congenital heart defects?
Congenital heart defects (CHD), the most common cause of birth defects with increasing
birth prevalence, affect nearly 1% of live births worldwide. Cyanotic CHD are characterized …
birth prevalence, affect nearly 1% of live births worldwide. Cyanotic CHD are characterized …
Recovery from experimental parkinsonism by intrastriatal application of erythropoietin or EPO-releasing neural precursors
S Carelli, T Giallongo, C Viaggi, E Latorre… - …, 2017 - Elsevier
An extensive literature has shown a powerful neuroprotective action of Erythropoietin (EPO)
both in vivo and in vitro. This study shows that EPO, whether ectopically administered or …
both in vivo and in vitro. This study shows that EPO, whether ectopically administered or …
[HTML][HTML] Activation of the EPOR-β common receptor complex by cibinetide ameliorates impaired wound healing in mice with genetic diabetes
A Bitto, N Irrera, G Pizzino, G Pallio, F Mannino… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Diabetes is characterized by poor wound healing which currently lacks an efficacious
treatment. The innate repair receptor (IRR) is a master regulator of tissue protection and …
treatment. The innate repair receptor (IRR) is a master regulator of tissue protection and …