Context-specific regulation of extracellular vesicle biogenesis and cargo selection
AC Dixson, TR Dawson, D Di Vizio… - … Reviews Molecular Cell …, 2023 - nature.com
To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …
other cells. An important aspect of cell–cell communication involves secretion of molecules …
[HTML][HTML] Extracellular vesicles remodel tumor environment for cancer immunotherapy
M Yue, S Hu, H Sun, B Tuo, B Jia, C Chen, W Wang… - Molecular Cancer, 2023 - Springer
Tumor immunotherapy has transformed neoplastic disease management, yet low response
rates and immune complications persist as major challenges. Extracellular vesicles …
rates and immune complications persist as major challenges. Extracellular vesicles …
[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that affects more
than 44 million people worldwide. Despite the high disease burden, there is no effective …
than 44 million people worldwide. Despite the high disease burden, there is no effective …
Biogenesis, membrane trafficking, functions, and next generation nanotherapeutics medicine of extracellular vesicles
S Gurunathan, MH Kang, M Qasim… - International Journal of …, 2021 - Taylor & Francis
Extracellular vesicles (EVs) are a heterogeneous group of membrane-limited vesicles and
multi-signal messengers loaded with biomolecules. Exosomes and ectosomes are two …
multi-signal messengers loaded with biomolecules. Exosomes and ectosomes are two …
[HTML][HTML] The exosome: a review of current therapeutic roles and capabilities in human reproduction
M Dimik, P Abeysinghe, J Logan, M Mitchell - Drug Delivery and …, 2023 - Springer
Abstract Exosomes are nano-vesicles (30–150 nm) which may be useful as therapeutic
delivery vehicles and as diagnostic biomarkers. Exosomes are produced naturally within the …
delivery vehicles and as diagnostic biomarkers. Exosomes are produced naturally within the …
[HTML][HTML] Tumor-derived extracellular vesicles as messengers of natural products in cancer treatment
Y Xu, K Feng, H Zhao, L Di, L Wang, R Wang - Theranostics, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are kinds of two-layer vesicles secreted by cells. They play
significant roles in mediating component exchange between cells, signal transduction, and …
significant roles in mediating component exchange between cells, signal transduction, and …
[HTML][HTML] Signaling pathways of EBV-induced oncogenesis
Y Luo, Y Liu, C Wang, R Gan - Cancer Cell International, 2021 - Springer
Epstein-Barr virus (EBV) is closely associated with multiple human cancers. EBV-associated
cancers are mainly lymphomas derived from B cells and T cells (Hodgkin lymphoma, Burkitt …
cancers are mainly lymphomas derived from B cells and T cells (Hodgkin lymphoma, Burkitt …
[HTML][HTML] Current understanding of extracellular vesicle homing/tropism
MJ Edelmann, PE Kima - Zoonoses (Burlington, Mass.), 2022 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are membrane-enclosed packets released from cells that can
transfer bioactive molecules from cell to cell without direct contact with the target cells. This …
transfer bioactive molecules from cell to cell without direct contact with the target cells. This …
[HTML][HTML] The forces driving cancer extracellular vesicle secretion
The discovery that cancer cells discharge vast quantities of extracellular vesicles (EVs),
underscored the explosion of the EV field. A large body of evidence now supports their onco …
underscored the explosion of the EV field. A large body of evidence now supports their onco …
[HTML][HTML] Integrative biology of extracellular vesicles in diabetes mellitus and diabetic complications
J Liu, Y Zhang, Y Tian, W Huang, N Tong, X Fu - Theranostics, 2022 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) is a chronic systemic disease with increasing prevalence globally.
An important aspect of diabetic pathogenesis is cellular crosstalk and information exchange …
An important aspect of diabetic pathogenesis is cellular crosstalk and information exchange …