Shaping faces: genetic and epigenetic control of craniofacial morphogenesis

L Selleri, FM Rijli - Nature Reviews Genetics, 2023 - nature.com
Major differences in facial morphology distinguish vertebrate species. Variation of facial
traits underlies the uniqueness of human individuals, and abnormal craniofacial …

[HTML][HTML] Decoding the human face: progress and challenges in understanding the genetics of craniofacial morphology

S Naqvi, H Hoskens, F Wilke… - Annual review of …, 2022 - annualreviews.org
Variations in the form of the human face, which plays a role in our individual identities and
societal interactions, have fascinated scientists and artists alike. Here, we review our current …

Genome-wide mapping of global-to-local genetic effects on human facial shape

P Claes, J Roosenboom, JD White, T Swigut, D Sero… - Nature …, 2018 - nature.com
Genome-wide association scans of complex multipartite traits like the human face typically
use preselected phenotypic measures. Here we report a data-driven approach to …

[HTML][HTML] A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia

K Adhikari, J Mendoza-Revilla, A Sohail… - Nature …, 2019 - nature.com
We report a genome-wide association scan in> 6,000 Latin Americans for pigmentation of
skin and eyes. We found eighteen signals of association at twelve genomic regions. These …

Identification of individuals by trait prediction using whole-genome sequencing data

C Lippert, R Sabatini, MC Maher… - Proceedings of the …, 2017 - National Acad Sciences
Prediction of human physical traits and demographic information from genomic data
challenges privacy and data deidentification in personalized medicine. To explore the …

Insights into the genetic architecture of the human face

JD White, K Indencleef, S Naqvi, RJ Eller, H Hoskens… - Nature …, 2021 - nature.com
The human face is complex and multipartite, and characterization of its genetic architecture
remains challenging. Using a multivariate genome-wide association study meta-analysis of …

[HTML][HTML] Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance

JC Chacón-Duque, K Adhikari… - Nature …, 2018 - nature.com
Historical records and genetic analyses indicate that Latin Americans trace their ancestry
mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan …

[HTML][HTML] Recent advances in Forensic DNA Phenotyping of appearance, ancestry and age

M Kayser, W Branicki, W Parson, C Phillips - Forensic Science International …, 2023 - Elsevier
Abstract Forensic DNA Phenotyping (FDP) comprises the prediction of a person's externally
visible characteristics regarding appearance, biogeographic ancestry and age from DNA of …

[HTML][HTML] ImaGene: a convolutional neural network to quantify natural selection from genomic data

L Torada, L Lorenzon, A Beddis, U Isildak, L Pattini… - BMC …, 2019 - Springer
Background The genetic bases of many complex phenotypes are still largely unknown,
mostly due to the polygenic nature of the traits and the small effect of each associated …

Genetic variants underlying differences in facial morphology in East Asian and European populations

M Zhang, S Wu, S Du, W Qian, J Chen, L Qiao… - Nature Genetics, 2022 - nature.com
Facial morphology—a conspicuous feature of human appearance—is highly heritable.
Previous studies on the genetic basis of facial morphology were performed mainly in …