Protocell fitness under extreme prebiotic conditions is critical in understanding the origin of
life. However, little is known about protocell's survival and fitness under prebiotic radiations …

Membrane enclosed intracellular compartments have previously been exclusively
associated with the eukaryotes, represented by the highly compartmentalized last eukaryotic …

Prominent among the models for protocells is the spherical biosurfactant shell, freely
suspended in aqueous media. This model explains initial, but not subsequent events in the …

In this perspective article, I discuss whether and how solid surfaces could have played a key
role in the formation of membranous primitive cells on the early Earth. I argue why surface …

We report the formation, growth, and dynamics of model protocell superstructures on solid
surfaces, resembling single cell colonies. These structures, consisting of several layers of …

We employ model protocell networks for evaluation of molecular transport through lipid
nanotubes as potential means of communication among primitive cells on the early Earth …

Coarse-grained (CG) Martini force field in molecular dynamics simulations is currently the
most popular model to study protein-lipid interactions for large protein size and long …

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Tunneling nanotubes are ubiquitous in long-distance communication in all domains of life.
Similarly, spontaneously formed lipid nanotubes could have allowed the transport of …

How primitive cells emerged and developed on the early Earth remain an unsolved
question. In contrast to the hypotheses that the first living cells evolved from a single …