Candida albicans—The Virulence Factors and Clinical Manifestations of Infection

J Talapko, M Juzbašić, T Matijević, E Pustijanac… - Journal of Fungi, 2021 - mdpi.com
Candida albicans is a common commensal fungus that colonizes the oropharyngeal cavity,
gastrointestinal and vaginal tract, and healthy individuals' skin. In 50% of the population, C …

The regulation of hyphae growth in Candida albicans

H Chen, X Zhou, B Ren, L Cheng - Virulence, 2020 - Taylor & Francis
In the last decades, Candida albicans has served as the leading causal agent of life-
threatening invasive infections with mortality rates approaching 40% despite treatment …

Mechanism of Candida pathogenesis: revisiting the vital drivers

IE Mba, EI Nweze - European Journal of Clinical Microbiology & Infectious …, 2020 - Springer
Candida is the most implicated fungal pathogen in the clinical setting. Several factors play
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …

We need to talk about Candida tropicalis: Virulence factors and survival mechanisms

MM Dos Santos, K Ishida - Medical mycology, 2023 - academic.oup.com
Candida tropicalis is a notable species of the Candida genus representing an impressive
epidemiology in tropical regions, especially in South America and Asia, where India already …

The role of Candida albicans stress response pathways in antifungal tolerance and resistance

KR Iyer, N Robbins, LE Cowen - Iscience, 2022 - cell.com
Human fungal pathogens are the causative agents of devastating diseases across the
globe, and the increasing prevalence of drug resistance threatens to undermine the already …

Adenylyl Cyclase and Protein Kinase A Play Redundant and Distinct Roles in Growth, Differentiation, Antifungal Drug Resistance, and Pathogenicity of Candida auris

JS Kim, KT Lee, MH Lee, E Cheong, YS Bahn - mbio, 2021 - Am Soc Microbiol
Candida auris is a globally emerging multidrug-resistant fungal pathogen. Its pathogenicity-
related signaling networks are largely unknown. Here, we characterized the pathobiological …

Adhesion and biofilm formation by the opportunistic pathogen Candida tropicalis: what do we know?

CM de Souza, MM Dos Santos… - Canadian journal of …, 2023 - cdnsciencepub.com
Candida tropicalis is among the most important Candida species in terms of epidemiology,
virulence and resistance. Considering the increase in C. tropicalis incidence and high rates …

Roles of alcohol dehydrogenase 1 in the biological activities of Candida albicans

Z Wang, Q Zhang, H Zhang, Y Lu - Critical Reviews in Microbiology, 2024 - Taylor & Francis
Candida albicans stands as the foremost prevalent human commensal pathogen and a
significant contributor to nosocomial fungal infections. In the metabolism of C. albicans …

cAMP signalling pathway in biocontrol fungi

ZB Sun, SF Yu, CL Wang, L Wang - Current Issues in Molecular Biology, 2022 - mdpi.com
Biocontrol is a complex process, in which a variety of physiological and biochemical
characteristics are altered. The cAMP signalling pathway is an important signal transduction …

Protein kinase A controls yeast growth in visible light

M Molin, K Logg, K Bodvard, K Peeters, A Forsmark… - BMC biology, 2020 - Springer
Background A wide variety of photosynthetic and non-photosynthetic species sense and
respond to light, having developed protective mechanisms to adapt to damaging effects on …