Well-differentiated/de-differentiated liposarcoma (WDLPS/DDLPS) is one of the most
common histologic subtypes of soft tissue sarcoma (STS); however, treatment options …

(1) Background: Glioblastoma is the most frequent and lethal primary tumor of the central
nervous system. Through many years, research has brought various advances in …

Abstract Proliferating Cell Nuclear Antigen (PCNA) is a highly conserved protein essential
for DNA replication, repair and scaffold functions in the cytosol. Specific inhibition of PCNA …

The genesis of cell-penetrating peptide research (CPP; also known as prote/peptide
transduction domains, PTD, or Trojan peptides) was born from the publication of two parallel …

This article discusses the studies on radiotherapy of high-grade gliomas published between
January 1, 2022, and June 30, 2022, with special reference to their molecular biology basis …

Glioblastoma (GBM) is the most common malignancy of the brain with a relatively short
median survival and high mortality. Advanced age, high socioeconomic status, exposure to …

The essential roles of proliferating cell nuclear antigen (PCNA) as a scaffold protein in DNA
replication and repair are well established, while its cytosolic roles are less explored. Two …

Hypocretin-1 is a multifunctional neuropeptide that has been identified as a potential
antitumor agent for its role in inhibiting tumor growth, including in colon cancer …

Despite enormous efforts being invested in the development of novel therapies for brain
malignancies, there remains a dire need for effective treatments, particularly for pediatric …

The efficacy of radiotherapy (RT) for non-small cell lung carcinoma (NSCLC) is often
compromised by radioresistance. Consequently, there is a pressing need for agents that can …