Nanogels: An overview of properties, biomedical applications and obstacles to clinical translation

KS Soni, SS Desale, TK Bronich - Journal of Controlled Release, 2016 - Elsevier
Nanogels have emerged as a versatile hydrophilic platform for encapsulation of guest
molecules with a capability to respond to external stimuli that can be used for a multitude of …

Stimuli-responsive nanogel composites and their application in nanomedicine

M Molina, M Asadian-Birjand, J Balach… - Chemical Society …, 2015 - pubs.rsc.org
Nanogels are nanosized crosslinked polymer networks capable of absorbing large
quantities of water. Specifically, smart nanogels are interesting because of their ability to …

Bioconjugated nanoparticles for biosensing, in vivo imaging, and medical diagnostics

BA Kairdolf, X Qian, S Nie - Analytical chemistry, 2017 - ACS Publications
Bioconjugated nanoparticles are of considerable current interest because materials on the
nanometer scale have unique optical, electronic, and magnetic properties with broad …

Polysaccharide-based nanogels for biomedical applications: A comprehensive review

F Damiri, S Rojekar, Y Bachra, RS Varma… - Journal of Drug Delivery …, 2023 - Elsevier
The biomedical, biotech, and food industries all use polysaccharides as vital biomolecules
with a variety of applications. Polysaccharides have a great deal of potential as biomaterials …

Advances in gadolinium-based MRI contrast agent designs for monitoring biological processes in vivo

J Lux, AD Sherry - Current opinion in chemical biology, 2018 - Elsevier
Highlights•Responsive MRI agents provide new insights into Zn 2+ ion release from
secretory tissues.•Small molecule targeted agents are sensitive enough to detect abundant …

Responsive crosslinked polymer nanogels for imaging and therapeutics delivery

AE Ekkelenkamp, MR Elzes, JFJ Engbersen… - Journal of Materials …, 2018 - pubs.rsc.org
Water-soluble, nano-sized crosslinked polymer networks, or nanogels, are delivery vehicles,
which have highly interesting properties for therapeutic delivery and imaging. Nanogels may …

Gadolinium-based nanoparticles for theranostic MRI-radiosensitization

F Lux, L Sancey, A Bianchi, Y Crémillieux, S Roux… - …, 2015 - Taylor & Francis
A rapid development of gadolinium-based nanoparticles is observed due to their attractive
properties as MRI-positive contrast agents. Indeed, they display high relaxivity, adapted …

Advantages of gadolinium based ultrasmall nanoparticles vs molecular gadolinium chelates for radiotherapy guided by MRI for glioma treatment

G Le Duc, S Roux, A Paruta-Tuarez, S Dufort… - Cancer …, 2014 - Springer
AGuIX nanoparticles are formed of a polysiloxane network surrounded by gadolinium
chelates. They present several characteristics. They are easy to produce, they present very …

Gadolinium-Loaded Poly(N-vinylcaprolactam) Nanogels: Synthesis, Characterization, and Application for Enhanced Tumor MR Imaging

W Sun, S Thies, J Zhang, C Peng, G Tang… - … applied materials & …, 2017 - ACS Publications
We report the synthesis of poly (N-vinylcaprolactam) nanogels (PVCL NGs) loaded with
gadolinium (Gd) for tumor MR imaging applications. The PVCL NGs were synthesized via …

Novel nanogels loaded with Mn (II) chelates as effective and biologically stable MRI probes

F Carniato, M Ricci, L Tei, F Garello, C Furlan… - Small, 2023 - Wiley Online Library
Here it is described nanogels (NG) based on a chitosan matrix, which are covalently
stabilized by a bisamide derivative of Mn‐t‐CDTA (t–CDTA= trans‐1, 2‐diaminocyclohexane …