Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

CD146 was originally identified as a melanoma cell adhesion molecule (MCAM) and highly
expressed in many tumors and endothelial cells. However, the evidence that CD146 acts as …

Immuno-positron emission tomography (immunoPET) is a molecular imaging modality
combining the high sensitivity of PET with the specific targeting ability of monoclonal …

Fluorescence imaging is an emerging technology that can provide real-time information
about the operating field during cancer surgery. Non-specific fluorescent agents, used for …

Molecular imaging is a biomedical research discipline that has quickly emerged to afford the
observation, characterization, monitoring, and quantification of biomarkers and biological …

Cyanine is a class of fluorescent dye with meritorious fluorescence properties and has
motivated numerous researchers to explore its imaging capabilities by miscellaneous …

Purpose Nivolumab is a human monoclonal antibody specific for programmed cell death-1
(PD-1), a negative regulator of T-cell activation and response. Acting as an immune …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer mortality worldwide.
Various imaging modalities provide important information about HCC for its clinical …

Near-infrared (NIR, 650–1700 nm) bioimaging has emerged as a powerful strategy in tumor
diagnosis. In particular, NIR-I fluorescence imaging (650–950 nm) has drawn more …

For melanoma resistant to molecularly targeted therapy and immunotherapy, new treatment
strategies are urgently needed. A molecularly targeted theranostic pair may thus be of …