[HTML][HTML] Pharmacological properties and underlying mechanisms of curcumin and prospects in medicinal potential
YS Fu, TH Chen, L Weng, L Huang, D Lai… - Biomedicine & …, 2021 - Elsevier
Curcumin, isolated from Curcuma longa L., is a fat-soluble natural compound that can be
obtained from ginger plant tuber roots, which accumulative evidences have demonstrated …
obtained from ginger plant tuber roots, which accumulative evidences have demonstrated …
Curcumin and type 2 diabetes mellitus: prevention and treatment
F Pivari, A Mingione, C Brasacchio, L Soldati - Nutrients, 2019 - mdpi.com
Type 2 diabetes mellitus (T2DM) is an ensemble of metabolic diseases that has reached
pandemic dimensions all over the world. The multifactorial nature of the pathology makes …
pandemic dimensions all over the world. The multifactorial nature of the pathology makes …
Methylglyoxal and its adducts: Induction, repair, and association with disease
SWT Lai, EDJ Lopez Gonzalez, T Zoukari… - Chemical research in …, 2022 - ACS Publications
Metabolism is an essential part of life that provides energy for cell growth. During metabolic
flux, reactive electrophiles are produced that covalently modify macromolecules, leading to …
flux, reactive electrophiles are produced that covalently modify macromolecules, leading to …
The molecular link between oxidative stress, insulin resistance, and type 2 diabetes: A target for new therapies against cardiovascular diseases
Abstract Type 2 Diabetes Mellitus (T2D) is a chronic disease with a pandemic incidence
whose pathogenesis has not yet been clarified. Raising evidence highlighted the role of …
whose pathogenesis has not yet been clarified. Raising evidence highlighted the role of …
[HTML][HTML] Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions
N Apostolova, F Iannantuoni, A Gruevska, J Muntane… - Redox biology, 2020 - Elsevier
Abstract Type 2 diabetes (T2D) is a very prevalent, multisystemic, chronic metabolic disorder
closely related to atherosclerosis and cardiovascular diseases. It is characterised by …
closely related to atherosclerosis and cardiovascular diseases. It is characterised by …
[HTML][HTML] Metformin beyond an anti-diabetic agent: A comprehensive and mechanistic review on its effects against natural and chemical toxins
A Malaekeh-Nikouei, S Shokri-Naei… - Biomedicine & …, 2023 - Elsevier
In addition to the anti-diabetic effect of metformin, a growing number of studies have shown
that metformin has some exciting properties, such as anti-oxidative capabilities, anticancer …
that metformin has some exciting properties, such as anti-oxidative capabilities, anticancer …
Can metformin exert as an active drug on endothelial dysfunction in diabetic subjects?
T Salvatore, PC Pafundi, R Galiero, L Rinaldi… - Biomedicines, 2020 - mdpi.com
Cardiovascular mortality is a major cause of death among in type 2 diabetes (T2DM).
Endothelial dysfunction (ED) is a well-known important risk factor for the development of …
Endothelial dysfunction (ED) is a well-known important risk factor for the development of …
The effects of antioxidants from natural products on obesity, dyslipidemia, diabetes and their molecular signaling mechanism
Obesity is a risk factor that leads to the development of other diseases such as dyslipidemia
and diabetes. These three metabolic disorders can occur simultaneously, hence, the …
and diabetes. These three metabolic disorders can occur simultaneously, hence, the …
Effects of turmeric (Curcuma longa) and its constituent (curcumin) on the metabolic syndrome: An updated review
Z Vafaeipour, BM Razavi, H Hosseinzadeh - Journal of integrative …, 2022 - Elsevier
Metabolic syndrome (MS) involves people with the following risk factors: obesity,
hypertension, high glucose level and hyperlipidemia. It can increase the risk of heart …
hypertension, high glucose level and hyperlipidemia. It can increase the risk of heart …
Importance of paraoxonase 1 (PON1) as an antioxidant and antiatherogenic enzyme in the cardiovascular complications of type 2 diabetes: Genotypic and phenotypic …
Y Shokri, A Variji, M Nosrati, A Khonakdar-Tarsi… - Diabetes research and …, 2020 - Elsevier
Oxidant–antioxidant imbalance is involved in the etiology of different diseases, including
cardiovascular diseases (CVDs), liver disorders, kidney diseases, cancers and diabetes …
cardiovascular diseases (CVDs), liver disorders, kidney diseases, cancers and diabetes …