Clinical impact of computational heart valve models

M Toma, S Singh-Gryzbon, E Frankini, Z Wei… - Materials, 2022 - mdpi.com
This paper provides a review of engineering applications and computational methods used
to analyze the dynamics of heart valve closures in healthy and diseased states …

Histopathological insights into mitral valve prolapse-induced fibrosis

MT Dieterlen, K Klaeske, R Spampinato… - Frontiers in …, 2023 - frontiersin.org
Mitral valve prolapse (MVP) is a cardiac valve disease that not only affects the mitral valve
(MV), provoking mitral regurgitation, but also leads to maladaptive structural changes in the …

An Anatomically Shaped Mitral Valve for Hemodynamic Testing

A Darwish, C Papolla, R Rieu, L Kadem - Cardiovascular engineering and …, 2024 - Springer
In vitro modeling of the left heart relies on accurately replicating the physiological conditions
of the native heart. The targeted physiological conditions include the complex fluid dynamics …

Left ventricular fibrosis and CMR tissue characterization of papillary muscles in mitral valve prolapse patients

RA Spampinato, M Marin-Cuartas… - … International Journal of …, 2024 - Springer
Purpose Mitral valve prolapse (MVP) is associated with left ventricle (LV) fibrosis, including
the papillary muscles (PM), which is in turn linked to malignant arrhythmias. This study aims …

Comparative Study of Single Opening&Closing and Continuous Pulsatile Flow Valve Tester

H Wang, Z Lu, Z Zhou, L Liu, Z He - Cardiovascular Engineering and …, 2024 - Springer
Purpose The purpose is to demonstrate the difference in closing volume fraction between
the single opening&closing valve tester (SOCVT) and continuous pulsatile flow valve tester …

Utilization of Engineering Advances for Detailed Biomechanical Characterization of the Mitral–Ventricular Relationship to Optimize Repair Strategies: A …

A van Kampen, JE Morningstar, G Goudot, N Ingels… - Bioengineering, 2023 - mdpi.com
The geometrical details and biomechanical relationships of the mitral valve–left ventricular
apparatus are very complex and have posed as an area of research interest for decades …

Mitral Valve Imaging and Biomechanics: A Workflow Towards Computational Modeling and Validation

S Stephens - 2023 - search.proquest.com
The mitral valve serves a critical role in healthy cardiac function by ensuring the
unidirectional flow of oxygenated blood from the left atrium into the left ventricle. It …