Abstract Study Objectives: Excessive daytime sleepiness (EDS) is highly prevalent in the
general population and is associated with occupational and public safety hazards. However …

Hypersomnia is commonly comorbid with depressive illness and is associated with
treatment resistance, symptomatic relapse, and functional impairment. This review highlights …

The sleep-wake cycle is a biological phenomena under the orchestration of
neurophysiological, neurochemical, neuroanatomical, and genetical mechanisms …

By some estimates, there are as many as twelve million psychopaths in the United States
alone. Cold-blooded, remorseless, and strangely charismatic, they commit at least half of all …

Objective The aim of this study was to examine a possible association between depressive
symptoms and a functional polymorphism (rs686) that modulates the regulation of DRD1 …

Neuropsychiatric disorders (NPDs) constitute a heavy burden on public health systems
around the world and studies have demonstrated that the negative impact of NPDs is larger …

Background Ischemic stroke (IS) is a leading cause of death and disability worldwide. As
genetic heritability for IS is estimated at about 35%-40%, the identification of genetic variants …

This protocol aims to characterize patients with dual disorders (DD; comorbid major
depression and schizophrenia) compared with patients with only a diagnosis of substance …

Sleep disturbance is a reported side effect of antidepressant drugs in children. Using a
nonhuman primate model of childhood selective serotonin reuptake inhibitor (SSRI) therapy …

ABSTRACT A polymorphism in the PER3 (period circadian clock 3) gene has been
associated with neuropsychiatric disorders and endophenotypes. We evaluated the possible …