Acid microenvironment in bone sarcomas
Simple Summary Although rare, malignant bone sarcomas have devastating clinical
implications for the health and survival of young adults and children. To date, efforts to …
implications for the health and survival of young adults and children. To date, efforts to …
Dual-mode tumor imaging using probes that are responsive to hypoxia-induced pathological conditions
Hypoxia in solid tumors is associated with poor prognosis, increased aggressiveness, and
strong resistance to therapeutics, making accurate monitoring of hypoxia important. Several …
strong resistance to therapeutics, making accurate monitoring of hypoxia important. Several …
Boosting quantification accuracy of chemical exchange saturation transfer MRI with a spatial–spectral redundancy‐based denoising method
Chemical exchange saturation transfer (CEST) is a versatile technique that enables
noninvasive detections of endogenous metabolites present in low concentrations in living …
noninvasive detections of endogenous metabolites present in low concentrations in living …
Learned spatiotemporal correlation priors for CEST image denoising using incorporated global‐spectral convolution neural network
Purpose To develop a deep learning‐based method, dubbed Denoising CEST Network
(DECENT), to fully exploit the spatiotemporal correlation prior to CEST image denoising …
(DECENT), to fully exploit the spatiotemporal correlation prior to CEST image denoising …
A brief history and future prospects of CEST MRI in clinical non-brain tumor imaging
Chemical exchange saturation transfer (CEST) MRI is a promising molecular imaging tool
which allows the specific detection of metabolites that contain exchangeable amide, amine …
which allows the specific detection of metabolites that contain exchangeable amide, amine …
Intraperitoneal Delivery of Iopamidol to Assess Extracellular pH of Orthotopic Pancreatic Tumor Model by CEST‐MRI
The extracellular pH (pHe) of solid tumors is often acidic, as a consequence of the Warburg
effect, and an altered metabolic state is often associated with malignancy. It has been shown …
effect, and an altered metabolic state is often associated with malignancy. It has been shown …
Deep Learning-Based Denoising of CEST MR Data: A Feasibility Study on Applying Synthetic Phantoms in Medical Imaging
KL Radke, B Kamp, V Adriaenssens, J Stabinska… - Diagnostics, 2023 - mdpi.com
Chemical Exchange Saturation Transfer (CEST) magnetic resonance imaging (MRI)
provides a novel method for analyzing biomolecule concentrations in tissues without …
provides a novel method for analyzing biomolecule concentrations in tissues without …
GlucoCEST MRI for the Evaluation Response to Chemotherapeutic and Metabolic Treatments in a Murine Triple-Negative Breast Cancer: A Comparison with[18F]F …
Purpose Triple-negative breast cancer (TNBC) patients have usually poor outcome after
chemotherapy and early prediction of therapeutic response would be helpful.[18F] F-FDG …
chemotherapy and early prediction of therapeutic response would be helpful.[18F] F-FDG …
Tumor pH Imaging Using Chemical Exchange Saturation Transfer (CEST)-MRI
DL Longo, E Pirotta, R Gambino, F Romdhane… - … : Methods and Protocols, 2023 - Springer
Magnetic resonance imaging (MRI) is a noninvasive imaging technique that allows for
physiological and functional studies of the tumor microenvironment. Within MRI, the …
physiological and functional studies of the tumor microenvironment. Within MRI, the …
MRI de-noising using improved unbiased NLM filter
The magnetic resonance images focus on soft tissues, and it is often necessary for
healthcare professionals to reach the final conclusion in clinical diagnosis. However, these …
healthcare professionals to reach the final conclusion in clinical diagnosis. However, these …