Asthma is a chronic respiratory disease that affects 339 million people worldwide and has a
considerable impact on the pediatric population. Asthma symptoms can be controlled by …

Rationale: Albuterol, a bronchodilator medication, is the first-line therapy for asthma
worldwide. There are significant racial/ethnic differences in albuterol drug response …

The classification of chronic pulmonary obstructive disease (COPD) into clinical and
pathophysiological subsets is not new, but increasing data is available on the relation of …

Identifying protein biomarkers for chronic obstructive pulmonary disease (COPD) has been
challenging. Most previous studies have used individual proteins or preselected protein …

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with reduced
quality of life and earlier mortality, but its pathogenesis and key genes are still unclear. In …

Introduction Static hyperinflation, a hallmark characteristic of some patients with chronic
obstructive pulmonary disease, is related to higher mortality and cardiovascular morbidity …

Single nucleotide polymorphisms (SNPs) in various genes have been shown to associate
with COPD, suggesting a role in disease pathogenesis. Sulfatase modifying factor (SUMF1) …

In COPD, chronic inflammation and exposure to irritants, such as cigarette smoke, lead to
the thickening of bronchial walls. This results from increased deposition of collagen and …

Asthma is a heterogeneous and multifactorial respiratory disease with an important impact
on childhood. Difficult-to-treat asthma is not uncommon among children, and it causes a …

Objective Motile cilia impairment is a common condition in patients with chronically inflamed
airways, such as is seen in nasal polyps (NPs). The mechanism underlying this pathogenic …