More than a marker: potential pathogenic functions of MAP2

RA DeGiosio, MJ Grubisha, ML MacDonald… - Frontiers in molecular …, 2022 - frontiersin.org
Microtubule-associated protein 2 (MAP2) is the predominant cytoskeletal regulator within
neuronal dendrites, abundant and specific enough to serve as a robust somatodendritic …

[HTML][HTML] Seizures in the developing brain: cellular and molecular mechanisms of neuronal damage, neurogenesis and cellular reorganization

IE Holopainen - Neurochemistry international, 2008 - Elsevier
Epilepsy is a common neurological disorder that occurs more frequently in children than in
adults. The extent that prolonged seizure activity, ie status epilepticus (SE), and repeated …

Failure of neuronal maturation in Alzheimer disease dentate gyrus

B Li, H Yamamori, Y Tatebayashi… - … of neuropathology & …, 2008 - academic.oup.com
The dentate gyrus, an important anatomic structure of the hippocampal formation, is one of
the major areas in which neurogenesis takes place in the adult mammalian brain …

Regulation of neural differentiation of ADMSCs using graphene‐mediated wireless‐localized electrical signals driven by electromagnetic induction

Z Guo, C Sun, H Yang, H Gao, N Liang… - Advanced …, 2022 - Wiley Online Library
Although adipose‐derived mesenchymal stem cells (ADMSCs) isolated from patients' fat are
considered as the most important autologous stem cells for tissue repair, significant …

Wireless Electrical Signals Induce Functional Neuronal Differentiation of BMSCs on 3D Graphene Framework Driven by Magnetic Field

H Gao, C Sun, S Shang, B Sun, M Sun, S Hu, H Yang… - ACS …, 2023 - ACS Publications
Bone marrow mesenchymal stem cells (BMSCs) are suggested as candidates for
neurodegeneration therapy by autologous stem cells to overcome the lack of neural stem …

Rapamycin reverses status epilepticus-induced memory deficits and dendritic damage

AL Brewster, JN Lugo, VV Patil, WL Lee, Y Qian… - PloS one, 2013 - journals.plos.org
Cognitive impairments are prominent sequelae of prolonged continuous seizures (status
epilepticus; SE) in humans and animal models. While often associated with dendritic injury …

Disruption of normal cytoskeletal dynamics may play a key role in the pathogenesis of epilepsy

J Gardiner, J Marc - The Neuroscientist, 2010 - journals.sagepub.com
Epilepsy, a common disease affecting 1% to 2% of the population, is characterized by
seizures, hyperexcitability at synapses, and aberrant extension of neurons following …

Spatiotemporal profile of Map2 and microglial changes in the hippocampal CA1 region following pilocarpine-induced status epilepticus

ND Schartz, SA Herr, L Madsen, SJ Butts, C Torres… - Scientific Reports, 2016 - nature.com
Status epilepticus (SE) triggers pathological changes to hippocampal dendrites that may
promote epileptogenesis. The microtubule associated protein 2 (Map2) helps stabilize …

Expression of Nampt in hippocampal and cortical excitatory neurons is critical for cognitive function

LR Stein, DF Wozniak, JT Dearborn… - Journal of …, 2014 - Soc Neuroscience
Nicotinamide adenine dinucleotide (NAD+) is an enzyme cofactor or cosubstrate in many
essential biological pathways. To date, the primary source of neuronal NAD+ has been …

Neuropsin promotes hippocampal synaptogenesis by regulating the expression and cleavage of L1CAM

B Barman, MK Thakur - Journal of Cell Science, 2024 - journals.biologists.com
During early postnatal brain development, the formation of proper synaptic connections
between neurons is crucial for the development of functional neural networks. Recent …