[HTML][HTML] The implication of gut microbiota in recovery from gastrointestinal surgery

Z Zheng, Y Hu, J Tang, W Xu, W Zhu… - Frontiers in Cellular and …, 2023 - frontiersin.org
Recovery from gastrointestinal (GI) surgery is often interrupted by the unpredictable
occurrence of postoperative complications, including infections, anastomotic leak, GI …

[HTML][HTML] Gut microbiota interactions with antitumor immunity in colorectal cancer: From understanding to application

YP Zhuang, HL Zhou, HB Chen, MY Zheng… - Biomedicine & …, 2023 - Elsevier
Colorectal cancer (CRC) is one of highly prevalent cancer. Immunotherapy with immune
checkpoint inhibitors (ICIs) has dramatically changed the landscape of treatment for many …

Male‐Biased Gut Microbiome and Metabolites Aggravate Colorectal Cancer Development

L Wang, YX Tu, L Chen, Y Zhang, XL Pan… - Advanced …, 2023 - Wiley Online Library
Men demonstrate higher incidence and mortality rates of colorectal cancer (CRC) than
women. This study aims to explain the potential causes of such sexual dimorphism in CRC …

[HTML][HTML] Fungal dysbiosis facilitates inflammatory bowel disease by enhancing CD4+ T cell glutaminolysis

M Yu, H Ding, S Gong, Y Luo, H Lin, Y Mu… - Frontiers in Cellular …, 2023 - frontiersin.org
The fungal microbiota is an important component of the complex multikingdom microbial
community colonizing the mammalian gastrointestinal tract and has an important role in …

Diet-induced shifts in the gut microbiota influence anastomotic healing in a murine model of colonic surgery

S Boatman, T Kaiser, H Nalluri-Butz, MH Khan… - Gut …, 2023 - Taylor & Francis
Host diet and gut microbiota interact to contribute to perioperative complications, including
anastomotic leak (AL). Using a murine surgical model of colonic anastomosis, we …

[HTML][HTML] Biodegradable high-nitrogen iron alloy anastomotic staples: In vitro and in vivo studies

S Lu, P Wang, Q Wang, P Deng, Y Yuan, X Fu, Y Yang… - Bioactive Materials, 2024 - Elsevier
For gastrointestinal anastomosis, metallic biodegradable staples have a broad application
potential. However, both magnesium and zinc alloys have relatively low strength to …

[HTML][HTML] Intestinal dysbiosis as an intraoperative predictor of septic complications: evidence from human surgical cohorts and preclinical models of peritoneal sepsis

D Spari, SN Zwicky, B Yilmaz, L Salm, D Candinas… - Scientific Reports, 2023 - nature.com
Major surgery exposes the intestinal microbiota to inflammatory and antibiotic stressors,
which alter the microbiota composition of the intestinal lumen and fecal contents. However, it …

The influence of gut microbiota on circulating inflammatory cytokines and host: a Mendelian randomization study with meta-analysis

F Xue, Z He, DZ Zhuang, F Lin - Life Sciences, 2023 - Elsevier
Aims The gut microbiota has been found to be altered in different inflammatory disorders, but
its involvement in the regulation of inflammatory cytokines remains unclear. Therefore, this …

The immunoregulatory role of gut microbiota in the incidence, progression, and therapy of breast cancer

K Xue, J Li, R Huang - Frontiers in Cellular and Infection Microbiology, 2024 - frontiersin.org
Breast cancer (BrCa) is the most prevalent malignant tumor in women and one of the
leading causes of female mortality. Its occurrence and progression are influenced by various …

Modulating gut microbiota prevents anastomotic leak to reduce local implantation and dissemination of colorectal cancer cells after surgery

R Hajjar, M Oliero, G Fragoso, AS Ajayi, AA Alaoui… - Clinical Cancer …, 2024 - AACR
Purpose: Anastomotic leak (AL) is a major complication in colorectal cancer surgery and
consists of the leakage of intestinal content through a poorly healed colonic wound …