Innovative nanomaterials for cancer diagnosis, imaging, and therapy: Drug delivery applications

M Pourmadadi, MM Eshaghi, S Ostovar… - Journal of Drug Delivery …, 2023 - Elsevier
The emergence of nanomedicine drugs as a result of the fast advancement of
nanotechnology offers enormous potential for improving cancer treatment strategies. The …

[HTML][HTML] Mitochondria deregulations in cancer offer several potential targets of therapeutic interventions

C Musicco, A Signorile, V Pesce… - International Journal of …, 2023 - mdpi.com
Mitochondria play a key role in cancer and their involvement is not limited to the production
of ATP only. Mitochondria also produce reactive oxygen species and building blocks to …

Recent advancement in therapeutic strategies for Alzheimer's disease: insights from clinical trials

T Khan, R Waseem, M Shahid, J Ansari… - Ageing Research …, 2023 - Elsevier
Alzheimer's disease (AD) is the most prevalent form of dementia, characterized by the
presence of plaques of amyloid beta and Tau proteins. There is currently no permanent cure …

Cell-permeable peptide-based delivery vehicles useful for subcellular targeting and beyond

K Stillger, I Neundorf - Cellular Signalling, 2023 - Elsevier
Personal medicine aims to provide tailor-made diagnostics and treatments and has been
emerged as a promising but challenging strategy during the last years. This includes the …

[HTML][HTML] Current advances in mitochondrial targeted interventions in Alzheimer's disease

T Sousa, PI Moreira, S Cardoso - Biomedicines, 2023 - mdpi.com
Alzheimer's disease is the most prevalent neurodegenerative disorder and affects the lives
not only of those who are diagnosed but also of their caregivers. Despite the enormous …

[HTML][HTML] The major hypotheses of Alzheimer's disease: related nanotechnology-based approaches for its diagnosis and treatment

C Cáceres, B Heusser, A Garnham, E Moczko - Cells, 2023 - mdpi.com
Alzheimer's disease (AD) is a well-known chronic neurodegenerative disorder that leads to
the progressive death of brain cells, resulting in memory loss and the loss of other critical …

[HTML][HTML] Mitochondrial dysfunction and therapeutic perspectives in osteoporosis

J Liu, Z Gao, X Liu - Frontiers in Endocrinology, 2024 - frontiersin.org
Osteoporosis (OP) is a systemic skeletal disorder characterized by reduced bone mass and
structural deterioration of bone tissue, resulting in heightened vulnerability to fractures due …

[HTML][HTML] The neuroprotective potential of phytochemicals in traumatic brain injury: mechanistic insights and pharmacological implications

GM Hasan, S Anwar, A Shamsi, SS Sohal… - Frontiers in …, 2024 - frontiersin.org
Traumatic brain injury (TBI) leads to brain damage, comprising both immediate primary
damage and a subsequent cascade of secondary injury mechanisms. The primary injury …

Investigating molecular interactions between human transferrin and resveratrol through a unified experimental and computational approach: Role of natural …

MS Khan, M Furkan, M Shahwan, DK Yadav, S Anwar… - Amino Acids, 2023 - Springer
Disruptions to iron metabolism and iron homeostasis have emerged as significant
contributors to the development and progression of Alzheimer's disease (AD). Human …

[HTML][HTML] Advances in mitochondria-targeted drug delivery

E Bottani, D Brunetti - Pharmaceutics, 2023 - mdpi.com
Mitochondria are dynamic organelles that play a crucial role in numerous cellular activities.
Their primary function is to convert the energy stored in nutrients into adenosine …