Detecting co-selection through excess linkage disequilibrium in bacterial genomes

S Mallawaarachchi, G Tonkin-Hill… - NAR Genomics and …, 2024 - academic.oup.com
Population genomics has revolutionized our ability to study bacterial evolution by enabling
data-driven discovery of the genetic architecture of trait variation. Genome-wide association …

Host ecology regulates interspecies recombination in bacteria of the genus Campylobacter

E Mourkas, K Yahara, SC Bayliss, JK Calland… - Elife, 2022 - elifesciences.org
Horizontal gene transfer (HGT) can allow traits that have evolved in one bacterial species to
transfer to another. This has potential to rapidly promote new adaptive trajectories such as …

Small RNAs that target G‐rich sequences are generated by diverse biogenesis pathways in Epsilonproteobacteria

SL Svensson, CM Sharma - Molecular Microbiology, 2022 - Wiley Online Library
Bacterial small RNAs (sRNAs) are widespread post‐transcriptional regulators that control
bacterial stress responses and virulence. Nevertheless, little is known about how they arise …

Multiple hypervirulent methicillin-sensitive Staphylococcus aureus lineages contribute towards poor patient outcomes in orthopedic device-related infections

V Post, B Pascoe, E Mourkas, JK Calland… - medRxiv, 2022 - medrxiv.org
Staphylococci are the most common cause of orthopedic device-related infections (ODRIs),
with Staphylococcus aureus responsible for a third or more of cases. This prospective …