Serum amyloid A (SAA) subtypes 1–3 are well-described acute phase reactants that are
elevated in acute inflammatory conditions such as infection, tissue injury, and trauma, while …

The very first line of defense in humans is innate immunity, serving as a critical strongpoint in
the regulation of inflammation. Abnormalities of the innate immunity machinery make up a …

Background The objective of this initiative was to develop a treat-to-target (T2T) approach for
the management of patients with Familial Mediterranean Fever (FMF), including the …

The aim of this study was to analyze the pregnancy process, especially the Familial
Mediterranean fever (FMF) disease course and attack types during pregnancy, and to …

Objective Inflammation has been associated with an increased risk for cancer development,
while innate immune system activation could counteract the risk for malignancies. Familial …

The innate immune system is critically involved in the pathogenesis of familial
Mediterranean fever (FMF), characterized by dysregulated inflammasome activity and …

Objectives There is no consensus on canakinumab treatment tapering and discontinuation
strategies in colchicine-resistant FMF patients. In this study, we aimed to establish a …

Chronic kidney disease (CKD) is a progressive and incurable disease that impairs kidney
function. Its prevalence is estimated to affect up to 800 million individuals within the general …

The objectives of this study were to investigate the clinical biological and histological renal
involvement secondary to familial Mediterranean fever (FMF), the epidemiological data …

We aimed to evaluate the effect of a combination of natural products on parameters related
to inflammation, endothelial dysfunction, and oxidative stress in a cohort of familial …