Risk factors of Lung Cancer in nonsmoker

N Akhtar, JG Bansal - Current problems in cancer, 2017 - Elsevier
Generally, the cause of lung cancer is attributed to tobacco smoking. But many of the new
lung cancer cases have been reported in nonsmokers. Apart from smoking; air pollution …

Epidemic of lung cancer in patients with HIV infection

TA Winstone, SFP Man, M Hull, JS Montaner, DD Sin - Chest, 2013 - Elsevier
The survival of patients with HIV infection has improved dramatically over the past 20 years,
largely owing to a significant reduction in opportunistic infections and AIDs-defining …

Integrative genomic analysis reveals somatic mutations in pheochromocytoma and paraganglioma

N Burnichon, L Vescovo, L Amar, R Libé… - Human molecular …, 2011 - academic.oup.com
Pheochromocytomas and paragangliomas are neuroendocrine tumors that occur in the
context of inherited cancer syndromes in∼ 30% of cases and are linked to germline …

microRNA-10b enhances pancreatic cancer cell invasion by suppressing TIP30 expression and promoting EGF and TGF-β actions

H Ouyang, J Gore, S Deitz, M Korc - Oncogene, 2014 - nature.com
Abstract Increased microRNA-10b (miR-10b) expression in the cancer cells in pancreatic
ductal adenocarcinoma (PDAC) is a marker of disease aggressiveness. In the present study …

Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression

R Kong, F Yi, P Wen, J Liu, X Chen… - The Journal of …, 2015 - Am Soc Clin Investig
Emerging evidence indicates that the neuronal guidance molecule SLIT plays a role in
tumor suppression, as SLIT-encoding genes are inactivated in several types of cancer …

Lung cancer in HIV infection

D Mani, M Haigentz Jr, DM Aboulafia - Clinical lung cancer, 2012 - Elsevier
Lung cancer is the most prevalent non–AIDS-defining malignancy in the highly active
antiretroviral therapy era. Smoking plays a significant role in the development of HIV …

Malathion induced cancer-linked gene expression in human lymphocytes

R Anjitha, A Antony, O Shilpa, KP Anupama… - Environmental …, 2020 - Elsevier
Background Malathion is the most widely used organophosphate pesticide in agriculture.
Increasing cancer incidence in agricultural workers and their children links to the exposure …

TRIM36, a novel androgen-responsive gene, enhances anti-androgen efficacy against prostate cancer by inhibiting MAPK/ERK signaling pathways

C Liang, S Wang, C Qin, M Bao, G Cheng, B Liu… - Cell Death & …, 2018 - nature.com
Hormone therapy drugs, such as bicalutamide and enzalutamide, directed against prostate
cancer focus on androgen receptor (AR) signaling and are initially effective, but the disease …

TIP30 regulates lipid metabolism in hepatocellular carcinoma by regulating SREBP1 through the Akt/mTOR signaling pathway

F Yin, G Sharen, F Yuan, Y Peng, R Chen, X Zhou… - Oncogenesis, 2017 - nature.com
Lipid reprogramming has been considered as a crucial characteristic in hepatocellular
carcinoma (HCC) initiation and progression. However, detailed molecular mechanisms have …

A novel TIP30 protein complex regulates EGF receptor signaling and endocytic degradation

C Zhang, A Li, X Zhang, H Xiao - Journal of Biological Chemistry, 2011 - ASBMB
Activated epidermal growth factor receptor (EGFR) continues to signal in the early
endosome, but how this signaling process is regulated is less well understood. Here we …