Microbial colonization of the infant occurs during a critical time window for immune and
gastrointestinal development. Infant colonization sets the stage for the adult microbiome …

Insulin resistance is a hallmark of obesity, diabetes, and cardiovascular diseases, and leads
to many of the abnormalities associated with metabolic syndrome. Our understanding of …

Background—Inflammation has been suggested as a risk factor for the development of
atherosclerosis. Recently, some components of the insulin resistance syndrome (IRS) have …

The work presented in this Endocrine Practice report reflects the commitment of the
American Association of Clinical Endocrinologists (AACE) and the American College of …

The ability of insulin to stimulate glucose uptake varies widely from person to person, and
these differences, as well as how the individual attempts to compensate for them, are of …

Background. Some studies have proposed chronic inflammation as an underlying biological
mechanism responsible for physical function decline in elderly people. The aim of this study …

Nearly 20 years ago, it was suggested that individuals exist who are not obese on the basis
of height and weight, but who, like people with overt obesity, are hyperinsulinemic, insulin …

South Asians are at higher risk than White Caucasians for the development of obesity and
obesity-related non-communicable diseases (OR-NCDs), including insulin resistance, the …

Insulin resistance is a uniform finding in type 2 diabetes, as are abnormalities in the
microvascular and macrovascular circulations. These complications are associated with …

Insulin resistance is increasingly recognized as a chronic, low-level, inflammatory state.
Hyperinsulinemia and insulin action were initially proposed as the common preceding …