Recent advances and future perspectives in the therapeutics of prostate cancer

GL Varaprasad, VK Gupta, K Prasad, E Kim… - … Hematology & Oncology, 2023 - Springer
Prostate cancer (PC) is one of the most common cancers in males and the fifth leading
reason of death. Age, ethnicity, family history, and genetic defects are major factors that …

Post-translational modifications that drive prostate cancer progression

I Samaržija - Biomolecules, 2021 - mdpi.com
While a protein primary structure is determined by genetic code, its specific functional form is
mostly achieved in a dynamic interplay that includes actions of many enzymes involved in …

Disabled-2, a versatile tissue matrix multifunctional scaffold protein with multifaceted signaling: Unveiling its potential in the cancer battle

NN Shah, BP Dave, KC Shah, DD Shah… - Naunyn-Schmiedeberg's …, 2024 - Springer
A multifunctional scaffold protein termed Disabled-2 (Dab2) has recently gained attention in
the scientific community and has emerged as a promising candidate in the realm of cancer …

[HTML][HTML] Identification of critical molecular factors and side effects underlying the response to thalicthuberine in prostate cancer: a systems biology approach

F Saberi, Z Dehghan, E Noori, Z Taheri… - Avicenna journal of …, 2023 - ncbi.nlm.nih.gov
Background: Uncontrolled mitosis of cancer cells and resistance cells to chemotherapy
drugs are the challenges of prostate cancer. Thalicthuberine causes a mitotic arrest and a …

Computational approaches for evaluation of isobavachin as potential inhibitor against t877a and w741l mutations in prostate cancer

RB Browne, N Goswami, P Borah… - Journal of Biomolecular …, 2023 - Taylor & Francis
Prostate cancer is the World's second most common cancer, with the fifth-highest male
mortality rate. Point mutations such as T877A and W741L are frequently seen in advanced …

A meta‐analysis of postoperative wound complications at the surgical site in prostate cancer patients undergoing robotic surgery

X Su, Z Dai, H Zhao, M Ji, Z Liu - International Wound Journal, 2024 - Wiley Online Library
This meta‐analysis critically evaluates the role of robotic surgery in reducing postoperative
wound complications in prostate cancer patients, comparing it with traditional open and …

Comprehensive landscape of STEAP family members expression in human cancers: unraveling the potential usefulness in clinical practice using integrated …

SM Rocha, S Socorro, LA Passarinha, CJ Maia - Data, 2022 - mdpi.com
The human Six-Transmembrane Epithelial Antigen of the Prostate (STEAP) family comprises
STEAP1-4. Several studies have pointed out STEAP proteins as putative biomarkers, as well …

[HTML][HTML] Molecular basis and therapeutic targets in prostate cancer: A comprehensive review

FC Militaru, V Militaru, N Crisan, IC Bocsan… - Biomolecules and …, 2023 - ncbi.nlm.nih.gov
Prostate cancer is one of the most significant causes of morbidity and mortality in male
patients. The incidence increases with age, and it is higher among African Americans. The …

Genetics of prostate carcinoma

B Krušlin, L Škara, T Vodopić, B Vrhovec, J Murgić… - 2021 - fulir.irb.hr
The aim of this review is to provide a brief overview of some current approaches regarding
diagnostics, pathologic features, treatment, and genetics of prostate carcinoma (PCa) …

Caveolin1: its roles in normal and cancer stem cells

X Lai, Y Guo, M Chen, Y Wei, W Yi, Y Shi… - Journal of Cancer …, 2021 - Springer
Purpose Stem cells are characterized by the capability of self-renewal and multi-
differentiation. Normal stem cells, which are important for tissue repair and tissue …