Pharmaceutical cocrystals are multicomponent systems composed of two or more molecules
and held together by H-bonding. Currently, cocrystals provide exciting opportunities in the …

Cocrystals are homogenous (single-phase) crystalline structures composed by two or more
components in a definite stoichiometric ratio bonded together by noncovalent bonds …

Originally discovered almost a century ago, cocrystals continue to gain interest in the
modern day due to their ability to modify the physical properties of solid-state materials …

Introduction: Hot-melt extrusion (HME) technology is applied successfully in the plastic,
rubber and food industry. HME has also emerged as an important technology for drug …

Design and synthesis of pharmaceutical cocrystals have received great interest in recent
years. Cocrystallization of drug substances offers a tremendous opportunity for the …

Hot melt extrusion has been a widely used process in the pharmaceutical area for three
decades. In this field, it is important to optimize the formulation in order to meet specific …

Oral administration of drugs is preferred over other routes for several reasons: it is non-
invasive, easy to administer, and easy to store. However, drug formulation for oral …

Thermal processing has gained much interest in the pharmaceutical industry, particularly for
the enhancement of solubility, bioavailability, and dissolution of active pharmaceutical …

Non-covalent derivatives (NCDs) are formed by incorporating one (or more) coformer
molecule (s) into the matrix of a parent molecule via non-covalent forces. These forces can …

Cocrystallization is an old technique and remains the focus of several research groups
working in the field of Chemistry and Pharmacy. This technique is basically in field for …