Regulation of antioxidant enzymes: a significant role for melatonin

C Rodriguez, JC Mayo, RM Sainz… - Journal of pineal …, 2004 - Wiley Online Library
Antioxidant enzymes form the first line of defense against free radicals in organisms. Their
regulation depends mainly on the oxidant status of the cell, given that oxidants are their …

Antioxidant systems and oxidative stress in the testes

RJ Aitken, SD Roman - Molecular mechanisms in spermatogenesis, 2008 - Springer
Spermatogenesis is an extremely active replicative process capable of generating approxi
mately 1,000 sperm a second. The high rates of cell division inherent in this process imply …

Melatonin: reducing the toxicity and increasing the efficacy of drugs

RJ Reiter, D Tan, RM Sainz, JC Mayo… - Journal of Pharmacy …, 2002 - Wiley Online Library
Abstract Melatonin (N‐acetyl‐5‐methoxytryptamine) is a molecule with a very wide
phylogenetic distribution from plants to man. In vertebrates, melatonin was initially thought to …

Melatonin mitigates mitochondrial malfunction

J Leon, D Acuña‐Castroviejo… - Journal of pineal …, 2005 - Wiley Online Library
Melatonin, or N‐acetyl‐5‐methoxytryptamine, is a compound derived from tryptophan that is
found in all organisms from unicells to vertebrates. This indoleamine may act as a protective …

Melatonin and mitochondrial function

J Leon, D Acuña-Castroviejo, RM Sainz, JC Mayo… - Life sciences, 2004 - Elsevier
Melatonin is a natural occurring compound with well-known antioxidant properties. In the
last decade a new effect of melatonin on mitochondrial homeostasis has been discovered …

New perspectives in melatonin uses

A Carpentieri, GD De Barboza, V Areco… - Pharmacological …, 2012 - Elsevier
This review summarizes the metabolism, secretion, regulation and sites of action of
melatonin. An updated description of the melatonin receptors, including their signal …

Ameliorative effect of melatonin against gamma-irradiation-induced oxidative stress and tissue injury

MA El-Missiry, TA Fayed, MR El-Sawy… - … and environmental safety, 2007 - Elsevier
While radiation hazards, due to free radical generation, present an enormous challenge for
biological and medical safety, melatonin is a potent scavenger of a variety of free radicals …

The potential of melatonin in reducing morbidity–mortality after craniocerebral trauma

MD Maldonado, F Murillo‐Cabezas… - Journal of pineal …, 2007 - Wiley Online Library
Craniocerebral trauma (CCT) is the most frequent cause of morbidity–mortality as a result of
an accident. The probable origins and etiologies are multifactorial and include free radical …

Lactobacillus fermentum Suo Attenuates HCl/Ethanol Induced Gastric Injury in Mice through Its Antioxidant Effects

H Suo, X Zhao, Y Qian, P Sun, K Zhu, J Li, B Sun - Nutrients, 2016 - mdpi.com
The purpose of the study was to determine the inhibitory effects of Lactobacillus fermentum
Suo (LF-Suo) on HCl/ethanol induced gastric injury in ICR (Institute for Cancer Research) …

Protective effect of silkworm pupa oil on hydrochloric acid/ethanol‐induced gastric ulcers

X Long, X Zhao, W Wang, Y Zhang… - Journal of the …, 2019 - Wiley Online Library
BACKGROUND Silkworm pupae are a traditional Chinese food, rich in various saturated
and unsaturated fatty acids. Unsaturated fatty acids have a certain protective effect against …