Chemical and biomolecular strategies for STING pathway activation in cancer immunotherapy
KM Garland, TL Sheehy, JT Wilson - Chemical reviews, 2022 - ACS Publications
The stimulator of interferon genes (STING) cellular signaling pathway is a promising target
for cancer immunotherapy. Activation of the intracellular STING protein triggers the …
for cancer immunotherapy. Activation of the intracellular STING protein triggers the …
[HTML][HTML] Towards principled design of cancer nanomedicine to accelerate clinical translation
Nanotechnology in medical applications, especially in oncology as drug delivery systems,
has recently shown promising results. However, although these advances have been …
has recently shown promising results. However, although these advances have been …
[HTML][HTML] A review of existing strategies for designing long-acting parenteral formulations: Focus on underlying mechanisms, and future perspectives
The need for long-term treatments of chronic diseases has motivated the widespread
development of long-acting parenteral formulations (LAPFs) with the aim of improving drug …
development of long-acting parenteral formulations (LAPFs) with the aim of improving drug …
Challenges and opportunities in metastatic breast cancer treatments: Nano-drug combinations delivered preferentially to metastatic cells may enhance therapeutic …
Despite advances in breast cancer treatments and related 5-year survival outcomes,
metastatic breast cancer cures remain elusive. The current standard of care includes a …
metastatic breast cancer cures remain elusive. The current standard of care includes a …
Recent advances in long-acting nanoformulations for delivery of antiretroviral drugs
In spite of introduction of combination antiretroviral therapy (cART) against human
immunodeficiency virus (HIV) infection; inaccessibility and poor adherence to oral cART …
immunodeficiency virus (HIV) infection; inaccessibility and poor adherence to oral cART …
Mesoporous platinum nanoparticle-based nanoplatforms for combined chemo-photothermal breast cancer therapy
B Fu, M Dang, J Tao, Y Li, Y Tang - Journal of colloid and interface science, 2020 - Elsevier
High-efficiency cancer treatment remains the main challenge at present. In this study, a
mesoporous platinum nanoparticle-(mesoPt) based nanoplatform is exported for effective …
mesoporous platinum nanoparticle-(mesoPt) based nanoplatform is exported for effective …
Nanoemulsions: The rising star of antiviral therapeutics and nanodelivery system—Current status and prospects
JS Franklyne, PM Gopinath, A Mukherjee… - Current Opinion in …, 2021 - Elsevier
Nanoemulsions (NEs) of essential oil (EO) have significant potential to target
microorganisms, especially viruses. They act as a vehicle for delivering antiviral drugs and …
microorganisms, especially viruses. They act as a vehicle for delivering antiviral drugs and …
Multifunctional nanomedicines for targeting epidermal growth factor receptor in colorectal cancer
Systemic administration of chemotherapeutics by nanocarriers (NCs) functionalized with
targeting agents provides a localized accumulation of drugs in the target tissues and cells …
targeting agents provides a localized accumulation of drugs in the target tissues and cells …
The promise of long-acting antiretroviral therapies: from need to manufacture
Antiretroviral therapy has transformed human immunodeficiency virus infections from certain
death to a manageable chronic disease. Achieving strict adherence to drug regimens that …
death to a manageable chronic disease. Achieving strict adherence to drug regimens that …
[PDF][PDF] Permanently Charged Cationic Lipids—Evolution from Excipients to Therapeutic Lipids
S Pushpa Ragini, R Banerjee, CJ Drummond… - Small Science, 2024 - d-nb.info
Complex diseases such as cancer and microbial infections are multifactorial in nature with
numerous redundant signalling pathways involved in the disease development.[1–3] …
numerous redundant signalling pathways involved in the disease development.[1–3] …