Chemical and biomolecular strategies for STING pathway activation in cancer immunotherapy

KM Garland, TL Sheehy, JT Wilson - Chemical reviews, 2022 - ACS Publications
The stimulator of interferon genes (STING) cellular signaling pathway is a promising target
for cancer immunotherapy. Activation of the intracellular STING protein triggers the …

[HTML][HTML] Towards principled design of cancer nanomedicine to accelerate clinical translation

M Souri, M Soltani, FM Kashkooli, MK Shahvandi… - Materials Today Bio, 2022 - Elsevier
Nanotechnology in medical applications, especially in oncology as drug delivery systems,
has recently shown promising results. However, although these advances have been …

[HTML][HTML] A review of existing strategies for designing long-acting parenteral formulations: Focus on underlying mechanisms, and future perspectives

Y Shi, A Lu, X Wang, Z Belhadj, J Wang… - … Pharmaceutica Sinica B, 2021 - Elsevier
The need for long-term treatments of chronic diseases has motivated the widespread
development of long-acting parenteral formulations (LAPFs) with the aim of improving drug …

Challenges and opportunities in metastatic breast cancer treatments: Nano-drug combinations delivered preferentially to metastatic cells may enhance therapeutic …

J Yu, Q Mu, M Fung, X Xu, L Zhu, RJY Ho - Pharmacology & therapeutics, 2022 - Elsevier
Despite advances in breast cancer treatments and related 5-year survival outcomes,
metastatic breast cancer cures remain elusive. The current standard of care includes a …

Recent advances in long-acting nanoformulations for delivery of antiretroviral drugs

DH Surve, AB Jindal - Journal of Controlled Release, 2020 - Elsevier
In spite of introduction of combination antiretroviral therapy (cART) against human
immunodeficiency virus (HIV) infection; inaccessibility and poor adherence to oral cART …

Mesoporous platinum nanoparticle-based nanoplatforms for combined chemo-photothermal breast cancer therapy

B Fu, M Dang, J Tao, Y Li, Y Tang - Journal of colloid and interface science, 2020 - Elsevier
High-efficiency cancer treatment remains the main challenge at present. In this study, a
mesoporous platinum nanoparticle-(mesoPt) based nanoplatform is exported for effective …

Nanoemulsions: The rising star of antiviral therapeutics and nanodelivery system—Current status and prospects

JS Franklyne, PM Gopinath, A Mukherjee… - Current Opinion in …, 2021 - Elsevier
Nanoemulsions (NEs) of essential oil (EO) have significant potential to target
microorganisms, especially viruses. They act as a vehicle for delivering antiviral drugs and …

Multifunctional nanomedicines for targeting epidermal growth factor receptor in colorectal cancer

M Akbarzadeh Khiavi, A Safary, J Barar… - Cellular and Molecular …, 2020 - Springer
Systemic administration of chemotherapeutics by nanocarriers (NCs) functionalized with
targeting agents provides a localized accumulation of drugs in the target tissues and cells …

The promise of long-acting antiretroviral therapies: from need to manufacture

HE Gendelman, JE McMillan, AN Bade, B Edagwa… - Trends in …, 2019 - cell.com
Antiretroviral therapy has transformed human immunodeficiency virus infections from certain
death to a manageable chronic disease. Achieving strict adherence to drug regimens that …

[PDF][PDF] Permanently Charged Cationic Lipids—Evolution from Excipients to Therapeutic Lipids

S Pushpa Ragini, R Banerjee, CJ Drummond… - Small Science, 2024 - d-nb.info
Complex diseases such as cancer and microbial infections are multifactorial in nature with
numerous redundant signalling pathways involved in the disease development.[1–3] …